Caliper Life Sciences, Inc.

Proterixbio, Inc.

Edward Marshall Alderman

Brett P Masters

Michael Francis Miller

Richard P Bunch

William Matthew Dickerson

Frederick D Simmons

In one non-limiting aspect, the invention provides a method for detecting the quality of a biological molecule comprising forming a first mixture of ingredients comprising: (i) a first binding agent that specifically binds to a tag, wherein the first binding agent is attached to a solid support; (ii) a decoy comprising a first portion comprising the tag attached to a second portion comprising an anchor; (iii) a sensor attached to a second binding agent that specifically binds to the anchor; and (iv) a sample suspected of containing a high quality biological molecule comprising a tag, wherein the tag of the high quality biological molecule is accessible; allowing interaction of the ingredients such that the sensor provides an output signal.

Methods and systems for the rapid characterization of functional biological molecules

A microtitre plate having a relieved perimeter includes a plate defining a plurality of wells and the perimeter of the plate is horizontally relieved. Alternatively, a microtitre plate may include a base and a holding section extending from the base. The holding section defines a plurality of wells and the perimeter thereof being horizontally relieved.

Microtitre plate with a relieved perimeter

Growing community of inventors

Framingham, MA, United States of America

Edward Marshall Alderman