Bio-rad Laboratories, Inc.

Varian, Inc.

Edward Marquette

Gregory J Wells

Matthew Aaron Alexander

Brian D Hall

Fan Xiong

Michelle Scott

Matthew Alexander

A circuit for sharing current between parallel LEDs or parallel strings of LEDs, and a method of use of the same, are disclosed herein. The circuit for sharing current between parallel LED pathways can include a first LED pathway, a first transistor coupled to the first set of LEDs and that can control a first current through the first set of LEDs, and a first measurement node having a first sensed voltage. The circuit can include a second LED pathway, a second transistor coupled to the second set of LEDs and that can control a second current through the second set of LEDs, and a second measurement node having a second sensed voltage. The circuit includes a first differential amplifier and a second differential amplifier, each of which can compare sensed voltage and can apply a voltage to a gate of one of the first and second transistors.

Circuit for sharing current between parallel LEDs or parallel strings of LEDs

An external fluidic system and methods of operating the same are provided. The fluidic system can be hot-swap connected to a flow-cytometer-based system at runtime to expand sheath or waste fluid storage capability of the flow-cytometer-based system by making only minimal changes to the flow-cytometer-based system. The external fluidic system can include a pump and a controller configured to operate the external fluidic system such that the sheath fluid is supplied from the external fluidic system to the flow-cytometer-based system or the waste fluid is extracted from the flow-cytometer-teased system and provided to the external fluidic system.

External fluidics system for flow cytometer

Disclosed is a system for setting the timing or phase of the separation of droplets from a fluid stream in a flow cytometer, or the timing or phase of a charge pulse generator, based upon the collected charge of charged droplets. In one embodiment, a conductive mesh can be used to collect the charged droplets that are either deflected or not deflected by the deflection plates. In another embodiment, the charge can be collected from metal plates in the waste collection device. In addition, a defanning device is disclosed that allows substantially uniform deflection of charged cells.

Timing and/or phase adjustment of the separation and/or charging of drops from a fluid stream in a flow cytometer

An electron source includes a first electrode, a second electrode, a thermionic element interposed between and electrically isolated from the first electrode and the second electrode, and a guard electrode interposed between and electrically isolated from the first electrode and the second electrode. The thermionic element and the guard electrode may be at substantially the same voltage. Another electron source includes a first electrode, a second electrode, a thermionic element interposed between and electrically isolated from the first electrode and the second electrode, and a thermal expansion component interposed between and electrically isolated from the first electrode and the second electrode. The thermal expansion component may be heated to cause expansion. The heating may be cycled to cause alternating expansion and contraction.

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Oakland, CA, United States of America

Edward Marquette