Metabolix, Inc.

Edward M Muller

Joseph Pugach

Luhua Zhong

James J Barber

Robert S Whitehouse

Daniel M Horowitz

Sean K Daughtry

Anna Egozy

Methods of forming intermediates from PHAs are disclosed.

Methods of making intermediates from polyhydroxyalkanoates

In some embodiments, this invention relates to a method that includes contacting a PHA with an aprotic catalyst to form an ester. The ester has only one monomer unit from the PHA. In certain embodiments, this invention relates to a method that includes treating a PHA-containing non-lyophilized biomass to form an ester, and removing at least some of the ester from the biomass.

Methods of forming intermediates from PHAs are disclosed. In general, the methods include forming a pyrrolidone from a PHA, such as poly 4-hydroxybutyrate or a 4-hydroxybutyrate containing polymer. The methods can include, for example, treating (e.g., heating) the PHA to form a pyrrolidone. The methods can include, for example, treating a biomass containing the PHA to form a pyrrolidone. The methods can include, for example, heating the PHA to a temperature of at most about 90&#xb0; C. to form a pyrrolidone, wherein the percent yield of the pyrrolidone is at least about 50%.

Molding compositions including polyhydroxyalkanoates are provided. The use of polyhydroxyalkanoates as a binder in molding compositions provides improved binder removal in the finished molded product, and offers a wide range of physical properties suitable for use in a variety of processing conditions. The composition preferably includes a powdered material, such as a metal powder, ceramic powder, or blend, admixed with a polyhydroxyalkanoate binder. The compositions are useful in powder processing techniques, such as injection molding, slip casting, tape casting, or extrusion.

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Westport, CT, United States of America

Edward M Muller