Merck + Co., Inc.

Edward L Paul

Roy W Grabner

William J McAleer

Mauricio Futran

Michael Midler, Jr

Shih-Hsie Pan

Paul D Liu

Jaanpyng Hsu

Edwin F Whittington

Impinging fluid jet streams are used in a continuous crystallization process to achieve high intensity micromixing of fluids so as to form a homogeneous composition prior to the start of nucleation. This process permits direct crystallization of high surface area particles of high purity and stability.

Crystallization method to improve crystal structure and size

Use of a static mixing system element as a tissue culture propagator. The element comprises an assembly of parallel sheets shaped to provide a plurality of mixing cells wherein fluid entering a cell from two separate inlet channels is rearranged due to shearing and extensional forces and divided into two new outlet streams each of which leaves the mixing cell in a different direction from either inlet stream. The configuration of the device provides uniform flow across all surfaces for precise control of growth conditions and maximum cell growth.

Motionless mixer as cell culture propagator

Cell scraping device

Use of motionless mixer as cell culture propagator

Growing community of inventors

Chatham Township, NJ, United States of America

Edward L Paul