Abbott Laboratories Corporation

Other

Abbott Molecular Inc.

Edward K Pabich

Ronald L Marshall

John J Carrino

John A Salituro

Hong Yu

Matthew T Manlove

John D Burczak

Paul A Klonowski

Omar S Khalil

Stanley R Bouma

Uwe Spies

Laurie A Rinehardt

Polynucleotides useful for detectingand/orin a test sample, kits, a nucleic acid amplification method and detection method including the same.

Polynucleotides for the amplification and detection of chlamydia trachomatis and neisseria gonorrhoeae

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Polynucleotides useful for detectingin a test sample, kits, a nucleic acid amplification method and detection method including the same.

The present invention relates to oligonucleotide probes useful in detecting, e.g. by hybridization or the ligase chain reaction, Chlamydia trachomatis DNA in the presence of other related DNA. The present invention is also directed to methods of detecting Chlamydia trachomatis organisms in a sample using the ligase chain reaction.

Oligonucleotides specific for the MOMP gene sequence and methods for the

Oligonucleotides and methods for the detection of Chlamydia trachomatis

Oligonucleotides and methods for the detection of chlamydia trachomatis

An apparatus and method for detecting amplified target nucleic acid is provided wherein the presence and concentration of amplified target is determined by total internal reflection over the course of the amplification reaction. A method and apparatus for detecting target nucleic acid is also provided wherein the presence and concentration of target is determined by total internal reflection and coupling of the target to the TIR element by scissile linkage. An improved immunoassay using total internal reflection and differential temperature cycling is further provided.

Method for detection of nucleic acid using total internal reflectance

The present invention relates to improved LCR amplification schemes using at least one downstream probe modified at its 5' end to reduce or eliminate target independent amplification. The different modified probes, and kits containing them are also presented. Also presented is a method for detecting differences in nucleic acid sequences, with reduced target independent amplification, using the modified probes.

Detecting and amplifying target nucleic acids using exonucleolytic

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Chicago, IL, United States of America

Edward K Pabich