Medrad, Inc.

Bayer Healthcare LLC

Bayer Medical Care Inc.

University of Pennsylvania

Other

Bayer Pharma Aktiengesellschaft

Edward J Rhinehart

Kevin P Cowan

Arthur E Uber, Iii

Barry Tucker

Michael A Spohn

Mark Trocki

Mark W Hitchins

Alan D Hirschman

Rosemary Almon-Martin

David M Reilly

David M Griffiths

Francis J Sciulli, Jr

Frederick W Trombley, Iii

Karen M Zelenski

Walter Grumski

Anthony S McCoppin

John A Haury

Gerald W Callan

James Albert Dedig

John Francis Kalafut

George J Misic

Eugene A Gelblum

Joseph B Havrilla

John A Brosovich

Glen P Williams

Michael J Yanniello

Martin J Uram

David A Mishler

Mitchell D Schnall

Robert E Lenkinski

Klaus Urich

Dennis P Hack

Michael J Swantner

Ralph H Schriver

Samuel L Belcher

Matthew Beale

Raymond C Hoffman

Arthur Uber

Thomas R Welch

Timothy Newing

Robert Dale Parks

Yutaka Imai

Benjamin Thomas Krupp

John Matthew Puskar-Pasewicz

Steven J Remis

Douglas Descalzi

Scott Griffith

Vera Pagano

Robert J Masarik

Barry L Tucker

Arthur E Uber

James E Machek

James R Neill

Michael F Emig

Matthew Sass

Ronald Heller

Herbert Y Kressel

Benjamin Taggart

Thomas L Dufalla

Theodore C Claiborne

Iii Uber Arthur E

Martin J Gibler

Dave Berry

Steven C Rygg

Michelle Robinson

Howard M Pollack

David H Berry

Richard Dewit

Barton Milestone

Herbert Y Kresel

David Mishler

Jill Denesvich

Michael Yanniello

Martin Uram

John Puskar-Pascewicz

John Brosovich

Larry J Fuchs

Michael W Sanctis

James R Neil

Matthew Mcgee

Dave Callen

James A Dedig

Benjamin T Krupp

Arthur E Iii Uber

Arthur E Uber Iii

Frederick W Iii Trombley

Kathy Mccoppin

Bronwyn Uber

Paul Levin

A syringe retaining element protruding radially outward relative to an outer surface of a sidewall of a barrel of a syringe is described. The syringe retaining element is configured for interacting with a locking mechanism of a syringe port of a fluid injector to releasably retain the ring. Features of the syringe retaining element allow the syringe to be axially ejected from the syringe port upon rotation of the syringe. Other features of the syringe retaining element allow the syringe to engage the locking mechanism of the syringe port and rotationally guide the syringe into self-orienting alignment with the locking mechanism.

Self-orienting syringe and syringe interface

Systems and methods for intelligently delivering fluid to a targeted tissue are described. The systems and methods may include directing a pump to distribute fluid to a targeted tissue and receiving one or more signals from an intracorporeal sensing system, where the one or more signals correspond to one or more sensed feedback parameters at the targeted tissue. The systems and methods may also include determining whether the one or more sensed feedback parameters are within an acceptable range. If the one or more sensed feedback parameters are not within the acceptable range, the systems and methods may include determining an adjusted velocity for the plunger necessary to adjust the pressure of the fluid in the pump so that the one or more sensed feedback parameters move within the acceptable range and directing the pump to distribute the fluid at the adjusted velocity.

Medical fluid injector

A method of maintaining an overall flow rate during a sequential delivery of at least two fluids to a patient's blood vessel includes delivering at least a first fluid into the patient's blood vessel at a first flow rate, delivering at least a second fluid into the patient's blood vessel at a second flow rate, and adjusting at least one of a first flow profile of the first flow rate and a second flow profile of the second flow rate to dampen a transient increase in the overall flow rate during a transition between delivering one of the first fluid and the second fluid to delivering the other of the first fluid and the second fluid.

System and method for improved fluid delivery in multi-fluid injector systems

A syringe includes a barrel having a distal end, a proximal end, and a sidewall extending therebetween along a longitudinal axis. At least one engagement member protrudes from a terminal portion of the sidewall in a proximal direction along the longitudinal axis. The at least one engagement member tapers axially in a direction from the distal end toward the proximal end. The at least one engagement member is configured for engagement with a locking mechanism of a fluid injector to releasably lock the syringe with the fluid injector. A taper of the at least one engagement member is configured to rotationally guide the syringe into alignment with the locking mechanism and axially eject the syringe upon rotation of the syringe. The locking mechanism operatively engages the at least one engagement member regardless of an orientation of the syringe about the longitudinal axis relative to the injector.

A medical injector including at least one syringe port for engaging at least one syringe and having a locking mechanism. The locking mechanism enables the syringe to self-align with the syringe port for locking engagement upon insertion of the syringe into the syringe port and to axially eject the syringe from the port upon rotational disengagement of the syringe from the port.

A pressure jacket for use with a fluid injector includes a barrel having a distal end, a proximal end, and a sidewall extending between the distal end and the proximal end along a longitudinal axis. The pressure jacket includes at least one engagement member protruding from a terminal portion of the proximal end of the barrel in a proximal direction along the longitudinal axis. The at least one engagement member tapers axially in a direction from the distal end toward the proximal end of the barrel. The at least one engagement member engages with a locking mechanism on the fluid injector to releasably lock the pressure jacket with the fluid injector. A taper of the at least one engagement member rotationally guides the barrel into self-alignment with the locking mechanism and axially ejects the barrel upon rotation of the barrel about the longitudinal axis.

Self-orienting pressure jacket and pressure jacket-to-injector interface

A medical connector assembly for establishing a fluid connection between a first medical device and a second medical device includes a multi-use connector and a plurality of single-use connectors connected in series. The multi-use connector has a proximal end opposite a distal end along a longitudinal length thereof. The plurality of single-use connectors each have a proximal end opposite a distal end along a longitudinal length thereof. The distal end of the multi-use connector is releasably connected to the proximal end of a first of the serially-connected single-use connectors. When a second of the serially-connected single-use connectors is disconnected from the first single-use connector, the first single-use connector remains connected to the multi-use medical connector as a sterility retaining cover.

Sterility retaining medical connector assembly and method

A pressure jacket includes a barrel having a proximal end, a distal end, and a sidewall extending substantially circumferentially between the proximal end and the distal end along a longitudinal axis. The pressure jacket also includes at least one retaining member having at least one first lug protruding radially outward relative to an outer surface of the sidewall. The at least one first lug has at least one third surface tapered axially relative to the longitudinal axis of the barrel in a proximal direction. The at least one first lug is configured for engagement with a locking mechanism associated with a port on a fluid injector to releasably lock the pressure jacket with the fluid injector. At least a portion of the at least one third surface axially ejects the pressure jacket upon rotation of the pressure jacket about the longitudinal axis.

A system capable of monitoring a replaceable component is provided. The system includes a controller for controlling operation of the system; programming instructions according to which the system is configured to: accept input of a viable life for the component, calculate an accumulated amount of distress experienced by the component based on each set of previously collected use data associated with each previous use of the component, and determine, based in part on the accumulated amount of distress, a used portion of the viable life that the component has experienced as a result of the previous use(s) thereof and an unused portion of the viable life; and a feedback device configured to provide to an operator of the system an indication of at least one of the unused and used portions of the viable life of the component. Methods of monitoring a replaceable component of a system are also provided.

Systems for determining, and devices for indicating, viable life of replaceable components thereof and methods therefor

A syringe for a fluid delivery system includes a pressure jacket having a distal end, a proximal end, and a throughbore therebetween. The syringe further includes a rolling diaphragm having a proximal end with an end wall for engaging a plunger, a distal end received within the throughbore of the pressure jacket. A sidewall extends between the proximal end and the distal end of the rolling diaphragm along a longitudinal axis. At least a portion of one of the sidewall and the end wall has non-uniform thickness. At least a portion of the sidewall is flexible and rolls upon itself when acted upon by the plunger such that an outer surface of the sidewall at a folding region is folded in a radially inward direction as the plunger is advanced from the proximal end to the distal end of the rolling diaphragm.

Syringe with rolling diaphragm

Growing community of inventors

Monroeville, PA, United States of America

Edward J Rhinehart