Allied Corporation

Edward H Manahan

Divakaran Masilamani

This invention relates to a process for preparing keto-cyano alkane compounds by treating the corresponding alpha substituted cycloalkanone compound with oxygen and ammonia in the presence of a transition metal catalyst.

Catalytic method of preparing keto-cyano alkane compounds

Processes for the autoxidative cleavage of selected ketones such as C.sub.4 -C.sub.10 cycloalkanones having at least one hydrogen or at least one R group on a carbon alpha to the carbonyl carbon or aryl alkyl ketones having the formula III ##STR1## comprising contacting a liquid phase comprising said ketone with elemental oxygen gas, preferably air, in the presence of a pulverized alkali metal hydroxide at a temperature of no more than 50.degree. C. for a time sufficient to produce an oxidized product are disclosed. Preferred cycloalkanones, 2-alkyl- and 2-arylcyclohexanone are autoxidized in pulverized sodium hydroxide/dimethoxyethane to produce 6-alkyl- or 6-aryl-6-oxohexanoic acids, respectively.

Autoxidative cleavage of ketones in the presence of pulverized alkali

A process for preparing substituted or unsubstituted benzoxazoline compound by reacting ammonia, a cycloalkanone and oxygen in the presence of metal cations.

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Morris Plains, NJ, United States of America

Edward H Manahan