Cardiac Mariners, Inc.

Vioptix, Inc.

Medibeacon Inc.

Triple Ring Technologies, Inc.

Leland Stanford Junior University

Oximetrix, Inc.

Cequr Sa

Novaray Medical, Inc.

Kla Tencor Corporation

C. R. Bard, Inc.

Progenity, Inc.

Robert Bosch Start-up Platform North America, Llc, Series 1

Nova Ray, Inc.

Nucleusrx LLC

Edward Gerald Solomon

Kate LeeAnn Bechtel

Joseph A Heanue

Robert E Melen

Brian Patrick Wilfley

Tobias Funk

Todd Louis Harris

Jennifer Keating

Alan Baldwin

Peter J Fiekowsky

Scott Coleridge

Jack W Moorman

Kimberly Merritt Shultz

Brian Skillicorn

Mark Lonsinger

Winston Sun

Abigail A Moorhouse

Lester John Lloyd

Russell B Ford

Waldo Stephen Hinshaw

John W Wilent, Deceased

Norbert Joseph Pelc

Josh Star-Lack

Giovanni Pastrone

Chwen-Yuan Ku

Robert Farra

Rebecca Fahrig

Peter Holst

Hermanus Stephanus Pretorius

Augustus Percival Lowell

Robert E Alvarez

Winston Y Sun

Lawrence Smith

Kenneth Barnett

David Piper

Daniel J Rachlin

John F Heanue

Mitchell Lawrence Jones

Steven Paul Woodard

David Aitan Soltz

William Welch

David E Baker

Jacob A Wolf

Kaijen Hsiao

Audrey Steever

Sarah Osentoski

Jeffrey A Shimizu

Ye Yang

Peter E Loeffler

Brian P Wilfley

Projit Aon

Mark Lin

Nick C Leindecker

Michael Beebe

Douglas D Elliott

Augustus P Lowell

Vytas V Pazemenas

Laurence S Horndon

M Nasser Ghodsi

John W Wilent

Ashok Rakhit

Kimberly Schultz

Mansour A Saleki

Mansour Abraham Saleki

A laparoscopic medical device includes an oximeter sensor at its tip, which allows the making of oxygen saturation measurements laparoscopically. The device can be a unitary design, wherein a laparoscopic element includes electronics for the oximeter sensor at a distal end (e.g., opposite the tip). The device can be a multiple piece design (e.g., two-piece design), where some electronics is in a separate housing from the laparoscopic element, and the pieces (or portions) are removably connected together. The laparoscopic element can be removed and disposed of; so, the electronics can be reused multiple times with replacement laparoscopic elements. The electronics can include a processing unit for control, computation, or display, or any combination of these. However, in an implementation, the electronics can connect wirelessly to other electronics (e.g., another processing unit) for further control, computation, or display, or any combination of these.

Oximetry device with laparoscopic extension

Devices and methods for administering a medication in fluid form, the systems and methods including a basal flow path and a bolus flow path in parallel to the basal flow path. The bolus flow path includes a combined piston pump and rotatable valve. The piston pump is configured to prevent partial dosing of a bolus dose.

Devices and methods for providing a bolus dose in a microfluidic circuit of a pump

A method of assessment of renal function by monitoring a time-varying fluorescence signal emitted from a fluorescent agent from within a diffuse reflecting medium with time-varying optical properties is provided that includes using a renal monitoring system comprising at least one light source, at least one light detector, at least one optical filter, and at least one controller to provide a measurement data set comprising a plurality of measurement entries, each measurement data entry comprising at least two measurements obtained at one data acquisition time from a patient before and after administration of the fluorescent agent.

Method for non-invasive monitoring of fluorescent tracer agent with diffuse reflecting medium with time-varying optical properties

An automated urine-output-measurement system can include single-patient equipment and multi-patient equipment. The single-patient equipment can include a urinary catheter and a urine-collection system. The urine-collection system can include drainage tubing and a drainage receptacle. The multi-patient equipment can include a urine monitor. The urine monitor can include a housing having a cavity configured to house the drainage receptacle, a urine-measurement means for measuring urine-output into the drainage receptacle, and an integrated display screen configured to display patient information including measurements of the urine output. A method of the automated urine-output-measurement system can include placing the drainage receptacle in the urine monitor of the automated urine-output-measurement system, and confirming a volume of urine in the drainage receptacle with that indicated on the urine monitor once a patient has produced urine.

Automated urine output measurement systems and methods thereof

Wireless laparoscopic probe

A system includes an enclosure having a processor and a memory coupled to the processor. The enclosure includes a display coupled to the processor where the display is visible from an exterior of the enclosure; and a battery within the enclosure coupled to the processor and the display. The enclosure includes a probe tip coupled to an exterior of the enclosure. The probe tip includes first, second, and third sensor openings. A first distance between the first and second sensor openings is different than a second distance between the first and third sensor openings. The enclosure includes code stored in the memory where the code is executable by the processor, and includes code to receive first data associated with the first and second sensor openings, code to receive second data associated with the first and second sensor openings, and code to perform SRS using the first and the second data.

Wireless, handheld tissue oximetry device

Apparatus and associated methods relate to a connected pill dispenser configured to treat a patient's illness with a robotic arm adapted to deliver a prescribed medication dose to a patient in their home, analyze the patient's response to the dose based on various sensor inputs, automatically determine whether the patient took the medicine and send the provider the result of providing the medication dose to the patient. In an illustrative example, the patient may be a chronic, acute, or terminal illness patient. The medication dose may be, for example, a medication prescribed by a doctor to be taken in a specific amount at specific times. In some embodiments, the connected pill dispenser may automatically notify the patient when a medication dose is due. Various embodiments may determine if the patient consumed a medication dose based on machine vision, audio, or other sensor data, permitting caregiver notification of patient medication adherence, medication compliance, or non-adherence and sensor inputs as data on potential effectiveness and/or side effects.

Connected pill dispenser

Ingestible devices with a relatively large payload volume or sample volume, as well as related components, systems and methods, are disclosed.

Ingestible device with relatively large payload volume

An optical system includes a splitting optic configured to receive a light beam from a light source and form a set of light bands radiating from the optical system at predetermined angles relative to illuminate a scene. The optical system further includes a lens configured to project a field of view of the scene into a two-dimensional format. The optical system further includes an optical sensor arranged offset from the central axis of the lens to capture a segment of the field of view projected by the lens.

Optical system

Devices and methods for administering a medication in fluid form, the systems and methods including a basal flow path and a bolus flow path in parallel to the basal flow path. The bolus flow path includes an inlet check valve, a first outlet check valve downstream of the inlet check valve, and a piston pump disposed between the inlet check valve and the first outlet check valve. The piston pump is configured to prevent partial dosing of a bolus dose.

A method of monitoring a time-varying fluorescence signal emitted from a fluorescent agent from within a medium with time-varying optical properties is provided that includes providing a measurement data set that includes a plurality of measurement entries that include at least two measurements obtained from a patient before and after administration of the fluorescent agent. The measurements may include one or more of: a DRsignal detected by an unfiltered light detector during illumination by excitatory-wavelength light from first region adjacent to the diffuse reflecting medium; a Flr signal detected by a filtered light detector during illumination by excitatory-wavelength light; and a DRsignal detected by the unfiltered light detector during illumination by emission-wavelength light. The method further includes identifying a post-agent administration portion of the measurement data set; and transforming each Flr signal to an IF signal representing a detected fluorescence intensity emitted solely by the fluorescent agent.

Method for non-invasive monitoring of fluorescent tracer agent with diffuse reflection corrections

Growing community of inventors

Menlo Park, CA, United States of America

Edward Gerald Solomon