Isp Investments Inc.

Edward G Malawer

Kolazi S Narayanan

James P Cullen

Philip F Wolf

Colleen M Rocafort

Michael A Tallon

Susan Y Tseng

Laurence Senak

Chi-San Wu

William Drefko

Victor Kabanov

David K Hood

Moshe Gershenson

Yuanzhen Zhong

Robert M Ianniello

Ronald H Goehner, Jr

Peter J Brush

Robert S Elliott

John Pearson

What is described herein is an excipient for a pharmaceutical tablet which is a proliferous copolymer of vinyl pyrrolidone and vinyl acetate, to provide the tablet with rapid dissolution and disintegration properties, and, also reduced hygroscopicity.

Proliferous copolymer of vinyl pyrrolidone and vinyl acetate

What is described herein is a pharmaceutical excipient which is a proliferous copolymer of vinyl pyrrolidone and vinyl acetate, having advantageous dissolution and disintegration properties.

What is described herein is a crosslinked polyvinylpyrrolidone (PVPP) copolymer of vinyl pyrrolidone (VP) and monomer derived from 1-vinyl-3-(E)-ethylidene pyrrolidone (EVP).

Crosslinked polyvinylpyrrolidone (PVPP) copolymer of vinyl pyrrolidone

Homogeneous copolymers of 60-99 mole % of vinyl pyrrolidone (VP) and 1-40 mole % 2-methylene-1,3-dioxepane (MDO), preferably 85-95 mole % VP and 5-10 mole % MDO, having a K-value of about 30-50, and a Tg of about 124-138.degree. C., are described herein. The copolymers are hydrolytically degradable in aqueous acid or basic solutions and biodegradable.

Homogeneous copolymers containing vinyl pyrrolidone and

A prefilter bag for insertion into a standard filtration bag apparatus, having a filtration assembly comprising a seamless filter membrane having uniform pore openings preselected within the range of between about 2 and about 50 microns (.mu.) and a linearly channeled, non-deformable, semi-rigid liquid transport thermoplastic sheet in the form of a molded webbing or netting in contact with the upper surface of the filter membrane; said webbing having marginal edges which are coextensive with those of the membrane; said assembly adapted to be shaped by continuous winding of the assembly upon itself for 2 to 5 complete convolutions around a tubular mandrel so as to form a cylindrical tube or cone; the bottom of said cylinder being sealed to prevent liquid leakage and the top of said cylinder, forming a liquid inlet opening, being sealed to a retaining ring adapted to be inserted in, attached to or sealed to an outer, retaining ring of a non-wrapped filter bag. The inlet of the wrapped cylindrical bag is optionally fitted with vortex directing means to enhance a linearly tangential direction of the entering liquid against the walls of the inside membrane. The invention also pertains to a method for the fabrication and use of the present filtration bag.

Filter bag and process of manufacture

Stable, water-based formulations containing high levels of water insoluble UV protectants/insecticides are provided herein as sprayable microemulsions containing a film-forming polymer, e.g. Agrimer.RTM. VEMA ES 425 [poly(methyl vinyl ether-maleic acid monobutyl ester)]. The polymers are solubilized either by partial neutralization with a base, or by emulsification with appropriate emulsifiers. These formulations produce single phase, micro- or mini-emulsions (particle size&lt;1 micron) on dilution with water. The formulations are useful as UV protectants in veterinary use, for protection of UV-labile insecticides, and for 'pour on' applications.

Low VOC, sunscreen spray composition containing a hydrophobic,

A low volatile organic compounds hair spray microemulsion in the form of a stable, clear, single phase system in which the particles therein have a diameter of less than 1 micron, consisting essentially of, by weight,

Low VOC hair spray composition

A low volatile organic compound hair spray composition in the form of a stable, clear, single phase microemulsion in which the particles therein have a diameter of less than 1 micron, consisting essentially of by weight, (a) a butyl half-ester of a copolymer of maleic anhydride and ethyl vinyl ether in an amount of about 2-10%, optionally neutralized up to 20 mole %, (b) poly(methyl vinyl ether) as a surface active polymer in an amount of at least 0.75 to 1 part of (a); (c) a secondary surfactant that is a polyethoxylated glyceryl fatty acid ester in an amount of at least 0.1%, and which has a hydrophilic-hydrophobic balance of greater than 10, (d) ethanol in an amount of 20 to 50%, and (e) water to 100%.

A 0% VOC, single phase hair spray composition of a water-insoluble polymer wherein substantially all the particles therein have a diameter of less than 1 micron, i.e. a microemulsion.

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Wayne, NJ, United States of America

Edward G Malawer