Colgate Palmolive Company

Edward Eigen

Dina I Brachman

Edward A Tavss

Alexander J Simone

Claudia Froebe

Stuart D Friedman

Kenneth F Clark

Sidney Weiss

Victor Temnikow

David Z Twersky

Deodorant compositions and a method of inhibiting bacterial exoenzymes responsible for the production of steroidal axillary malodor. The method comprises the steps of providing a cosmetic vehicle and dissolving or suspending a deodorant active material which is an inhibitor of bacterial exoenzymes responsible for the production of steroidal axillary malodor therein to produce a deodorant composition. Aryl sulfatase and beta-glucuronidase are the primary bacterial exoenzymes responsible for producing steroidal axillary odor. The deodorant active materials are inhibitors of these exoenzymes and include Cu++, hexametaphosphate (SPORIX), D-glucaro-.tangle-solidup.-lactone, EDTA, NTA, O-phenanthroline, Sodium sulfate or orthophosphate. In an alternative embodiment of the invention, a cosmetic vehicle comprising inorganic acids, organic acids or water soluble metal salts of fatty acids is combined with a deodorant active material, selected from the group consisting of Zn++ compounds, which is an inhibitor of bacterial exoenzymes responsible for the production of steroidal axillary malodor. The deodorant active materials of the invention directly inhibit the bacterial exoenzymes responsible for the production of steroidal axillary malodor rather than neutralizing unpleasant odors through chemical interaction and indirect inhibition of bacterial growth. These materials may be dissolved or suspended in a cosmetic vehicle in the form of a soap, lotion, fluid, cream, gel stick, powder or spray to provide a deodorant composition to prevent axillary odor without disturbing the natural flora of the axilla.

Deodorant compositions comprising inhibitors of odor-producing axillary

Deodorant compositions and a method of inhibiting bacterial exoenzymes responsible for the production of steroidal axillary malodor. The deodorant composition contains a cosmetic vehicle comprising inorganic acids, organic acids or water soluble metal salts of fatty acids is combined with a deodorant active material, selected from the group consisting of Zn++ compounds, which is an inhibitor of bacterial exoenzymes responsible for the production of steroidal axillary malodor. The deodorant active materials of the invention directly inhibit the bacterial exoenzymes responsible for the production of steroidal axillary malodor rather than neutralizing unpleasant odors through chemical interaction and indirect inhibition of bacterial growth. These materials may be dissolved or suspended in a cosmetic vehicle in the form of a soap, lotion, fluid, cream, gel stick, powder or spray to provide a deodorant composition to prevent axillary odor without disturbing the natural flora of the axilla.

Plaque is inhibited and oral hygiene promoted including reduction in caries formation by dispersing emulsan in water and contacting the aqueous dispersion with dental surfaces. Emulsan may be dispersed in dental preparation toothpaste or mouthwash.

Control of dental plaque and caries using emulsan

Control of dental plaque and caries

A deodorant body cleansing composition in the form of a liquid or solid opaque bar, comprising a detergent and a specific carbohydrate capable of reducing the odor-causing bacterial population on the body (skin and/or hair), without the use of antimicrobials. The essential deodorant agent which is a group of carbohydrates specifically effective against the odor-causing bacteria on the skin and/or hair, are mannose, glucose, and oligomers thereof, i.e. dimers, trimers, and tetramers.

Non-antimicrobial deodorant cleansing composition

A liquid detergent composition containing an anionic surfactant and a minor amount of a water-soluble, positively charged, partially hydrolyzed, protein fraction containing a high concentration of basic amino acids, having an isoionic point greater than 7 and a Bloom gel value of zero which counters the irritation caused by said anionic surfactant without reducing its foaming and detergency properties.

Agent for reducing detergent irritation to skin and eyes

Novel high absorption body powder compositions comprising rice hulls ground to a particle fineness such that the material passes through a 200 mesh sieve, and preferably passes through a 325 mesh sieve, as the basic and main powder constituent.

Ground rice hulls in body powders

A dentifrice composition containing an anionic surfactant, and a minor amount of a water soluble positively charged protein hydrolysate having an isoionic point above 7, and a Bloom gel value of zero, selected from the group consisting of a protein hydrolysate fraction containing high concentrations of basic amino acids or a quaternary derivative of a protein hydrolysate, which counters the irritation to the oral tissue and reduces the bitterness caused by said anionic surfactant, without reducing its foaming and cleansing properties. The present invention relates to novel oral compositions which are substantially non-irritating to the oral tissue, comprising an anionic surfactant and a positively charged water soluble protein hydrolysate fraction containing a high concentration of basic amino acids or a quaternary derivative of a protein hydrolysate. The protein hydrolysate fraction is obtained by extraction from a partially hydrolyzed protein mixture by means of ion exchange separation with an anion exchange resin. The quaternary derivative is obtained by quaternizing a protein hydrolysate mixture by chemically modifying the available terminal amino groups of the protein.

Non-irritating dentifrice

A novel dentifrice composition containing rice hulls ground to a particle fineness which passes a 200 mesh sieve, preferably passes a 325 mesh sieve, as the essential abrasive in amounts less than 40% by weight of the total composition.

Dentifrice composition

Mild light duty detergent formulation including an anionic surfactant having skin irritating characteristics and an effective amount of a homopolymer of ethylene oxide to reduce said skin irritation.

Growing community of inventors

East Brunswick, NJ, United States of America

Edward Eigen