The University of Texas System

Eli Lilly and Company

The United States of America as Represented by the Department of

Edward Deorsey McGruder

Billy M Hargis

Lawrence C Creemer

John R DeLoach

Michael H Kogut

Janice Rhea Herring

Novel compounds and methods for preparing same, immunopotentiating compositions, and a method for potentiating the immune system of a host animal. The method comprises administering to the animal an effective amount of an immunopotentiating compound of Formula I or Formula II, or a physiologically acceptable salt.

Immunopotentiator agents

A method of combatting microbial infections, including Escherichia coli and Salmonella infections, in immature birds by in ovo administration of an immune lymphokine (ILK) containing preparation in an amount effective to combat microbial infections in immature birds. A method of combatting microbial infections in immature birds by upregulating the production of endogenous Interleukin-8 (IL-8) in the bird. A method of combatting microbial infections in immature birds by in ovo administration of immune lymphokine (ILK).

Method of treating birds

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Fishers, IN, United States of America

Edward Deorsey McGruder