Metabasis Therapeutics, Inc.

Idun Pharmaceuticals, Inc.

Idun Pharmacueticals, Inc.

Edward D Robinson

Mark D Erion

K Raja Reddy

Qun Dang

Srinivas Rao Kasibhatla

Bheemarao G Ugarkar

M Rami Reddy

Vincent Jacob Kalish

Donald Karanewsky

Donald S Karanewsky

Brett Ullman

Brett R Ullman

Prodrugs of formula I, their uses, their intermediates, and their method of manufacture are described: 

Prodrugs for phosphorus-containing compounds

Novel purine compounds of Formula 1, pharmaceutically acceptable prodrugs and salts thereof, and their use as fructose 1,6-bisphosphatase inhibitors. 

Purine inhibitors of fructose-1,6-bisphosphatase

This invention is directed to novel (substituted) acyl dipeptidyl ICE/ced-3 family inhibitor compounds. The invention is also directed to pharmaceutical compositions containing these compounds, as well as the use of such compositions in the treatment of patients suffering inflammatory, autoimmune and neurodegenerative diseases, for the prevention of ischemic injury, and for the preservation of organs that are to undergo a transplantation procedure.

(Substituted)acyl dipeptidyl inhibitors of the ICE/CED-3 family of cysteine proteases

Novel purine compounds of the Formula 1, pharmacuetically acceptable prodrugs and salts thereof, and their use as fructose 1,6-bisphosphatase inhibitors

Prodrugs of formula I, their uses, their intermediates, and their method of manufacturing are described:and pharmaceutically acceptable prodrugs and salts thereof.

Prodrugs of formula I, their uses, their intermediates, and their method of manufacture are described:

Prodrugs phosphorus-containing compounds

Novel purine compounds of the following structure and their use as fructose-1,6-bisphosphatase inhibitors is described.

Purine inhibitors of fructose 1,6-bisphosphatase

This invention is directed to novel (substituted)acyl dipeptidyl ICE/ced-3 family inhibitor compounds. The invention is also directed to pharmaceutical compositions containing these compounds, as well as the use of such compositions in the treatment of patients suffering inflammatory, autoimmune and neurodegenerative diseases, for the prevention of ischemic injury, and for the preservation of organs that are to undergo a transplantation procedure.

Growing community of inventors

San Diego, CA, United States of America

Edward D Robinson