Eli Lilly and Company

Edward C R Smith

Dennis Michael Zimmerman

Paul Leslie Ornstein

Hamideh Zarrinmayeh

Jason Scott Sawyer

Douglas Wade Beight

Macklin Brian Arnold

John Michael Morin, Jr

Buddy Eugene Cantrell

Daniel Jon Sall

Ho-Shen Lin

Michael Enrico Richett

Richard L Simon

Michael Dean Kinnick

Thomas John Bleisch

Tracey E McKennon

Philip Arthur Hipskind

Thomas Charles Britton

Stephen Richard Baker

Karen Lynn Lobb

William Thomas McMillen

Robert F Bruns, Jr

Ken Matsumoto

James Arthur Nixon

Ana Maria Escribano

Donald Paul Matthews

Matthew Joseph Fisher

Timothy Alan Shepherd

Theodore Goodson, Jr

Kumiko Takeuchi

Prabhakar Kondaji Jadhav

David Andrew Neel

James A Aikins

Winton Dennis Jones, Jr

Alexander Glenn Godfrey

Shawn Christopher Miller

Donald R Gehlert

Sean Patrick Hollinshead

Steven Lee Kuklish

Hong-Yu Li

Jonathan Edward Green

David Michael Bender

Eric George Tromiczak

Joseph P Tizzano

David Bleakman

Kevin Robert Fales

Ryan Thomas Backer

Jonathan Michael Yingling

James Jeffry Howbert

Todd Vincent Decollo

Anne Marie Nunes

This application relates to a substituted carboxamide compound of formula I, or a pharmaceutically acceptable salt thereof, as defined herein, a pharmaceutical composition thereof, and its use in treating pain.

Substituted carboxamides

The present invention provides a compound of the formula: Formula (I) or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising an effective amount of a compound of Formula (I) in combination with a suitable carrier, diluent, or excipient; and methods for treating physiological disorders, particularly frailty, osteoporosis, osteopenia, and male and female sexual dysfunction comprising administering to a patient in need thereof an effective amount of a compound of formula (I). 

Tetrahydrocarbazole derivatives useful as androgen receptor modulators

The present invention relates to novel sulphonamide derivatives, to processes for their preparation and to pharmaceutical compositions containing them.

Sulphonamide derivatives

Novel pyrrazole derivative compounds and their use as pharmaceutical agents, in particular their use as TGF-beta signal transduction inhibitors. The disclosed invention relates to compounds of the structure (I) wherein (I) is a four, five, or six membered saturated ring and X is C, O or S

Pyrrole derivatives as pharmaceutical agents

A novel class of cycloalkyl fused indole compounds is disclosed together with the use of such compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of Inflammatory Diseases such as septic shock.

sPLA2 inhibitors

A novel class of benz[f]indole compounds is disclosed together with the use of such compounds for inhibiting sPLAmediated release of fatty acids for treatment of Inflammatory Diseases such as septic shock.

A novel class of benz[g]indole compounds is disclosed together with the use of such compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of Inflammatory Diseases such as septic shock.

Spla2 inhibitors

The invention relates to novel heterocycle substituted diphenyl leukotriene B (LTB ) antagonists, to compositions containing such compounds, and to methods of using such compounds for treatment of inflammatory diseases.

Heterocycle substituted diphenyl leukotriene antagonists

A class of novel substituted pyrrole is disclosed together with the use of such compounds for inhibiting sPLA mediated release of fatty acids for treatment of Inflammatory Diseases such as septic shock.

The present invention relates to the potentiation of glutamate receptor function using certain sulphonamide derivatives. It also relates to novel sulphonamide derivatives, to processes for their preparation and to pharmaceutical compositions containing them.

The present invention provides certain cyclopentyl sulfonamide derivatives of formula (I): useful for potentiating glutamate receptor function in a mammal. It also relates to novel cyclopentyl sulfonamide derivatives, to processes for their preparation and to pharmaceutical compositions containing them.

Cyclopentyl sulfonamide derivatives

The present invention relates to the potentiation of glutamate receptor function using certain 2-propane-sulphonamide derivatives. It also relates to novel 2-propane-sulphonamide derivatives, to processes for their preparation and to pharmaceutical compositions containing them.

2-propane-sulphonamide derivatives

The present invention provides certain sulfonamide derivatives useful for potentiating glutamate receptor function in a mammal and therefore, useful for treating a wide variety of conditions, such as psychiatric and neurological disorders.

Sulfonamide derivatives

Growing community of inventors

Fishers, IN, United States of America

Edward C R Smith