Other

Astra Pharmaceutical Products, Inc.

Edward A Tischlinger

Bengt Eve Hansson

A self injector having a spring powered gun assembly including a plunger rod driven forwardly by a compressed spring which is releasable by a retainer member to fire the plunger rod, and a cartridge assembly connected to said gun assembly, the cartridge assembly comprising a cylindrical shield connected to the gun assembly, a cartridge slidably positioned within the shield and including a cartridge tube with a slidable plunger closing off one end and a flexible diaphragm closing off the other to form a medicament chamber therebetween. A nose piece is affixed to the diaphragm end of the cartridge tube and mounts a cannula on its outside portion in fluid communication with the area on the cannula side of the diaphragm. The plunger rod is aligned with the cartridge plunger whereby when the gun is fired the plunger rod will push the plunger forwardly in the cartridge tube to cause the flexible diaphragm to contact and be pierced by a spike in the cartridge tube thereby establishing fluid communication between the medicament chamber and the cannula for injection purposes.

Self injector

A disposable medicament injector having a cylindrical barrel closed at one end by a slidable plunger and at the other end by a nose cap and diaphragm assembly including a flexible and pierceable wall defining a medicament chamber between the plunger and the flexible wall. A spike is positioned in spaced relation to the flexible wall whereby movement of the plunger will cause the medicament in the medicament chamber to flex the flexible wall of the diaphragm toward the spike which will then pierce the flexible wall to establish fluid communication between the medicament chamber and the area on the other side of the flexible wall.

Nose cap and diaphragm assembly for injector

A disposable additive syringe having a cylindrical barrel closed at the rear end by a slidable plunger and at the front end by a diaphragm assembly including a flexible and pierceable wall defining a medicament chamber between the plunger and the flexible wall. A cap and spike assembly mounted on the front end of the cylindrical barrel, said spike being positioned so that its end will be spaced from and outside the flexible wall and having a passage therethrough, a cannula extending forwardly from the cap and in fluid communication with the spike, a cylindrical safety guide extending forwardly from the cap and surrounding the cannula, a spike mounted by the safety guide and in fluid communication with the cannula, and a sheath supported by and covering the spike.

Disposable additive syringe

A mixing and dispensing disposable medicament injector having a cylindrical barrel closed at one end by a slidable plunger and at the other end by a first diaphragm assembly including a flexible wall. A second diaphragm assembly is positioned within the barrel intermediate the ends thereof to divide the barrel into two sealed chambers, a first chamber between the plunger and second diaphragm assembly being adapted to contain a liquid and a second chamber between the second diaphragm assembly and the first diaphragm assembly being adapted to contain a medicament in dry form. The second diaphragm assembly has a rupturable flexible wall to allow liquid to flow into the second chamber and the flexible wall in the first diaphragm assembly being rupturable to allow the mixed liquid medicament to be dispersed from the injector through the cannula fluidly connected to the first diaphragm assembly.

Mixing and dispensing disposable medicament injector

A medicament dispensing unit having a cylindrical barrel closed at one end by a slidable plunger is provided at the other end with a diaphragm assembly including a flexible wall defining a medicament chamber between the plunger and flexible wall. A needle is positioned in spaced relation to the flexible wall whereby movement of the plunger will cause the medicament to flex the flexible wall toward the needle which will then pierce the wall to establish fluid communication between the medicament chamber and the area at the other end of the needle. A finger grip is located on the plunger end of the barrel while a nose cap assembly is affixed to the diaphragm end of the barrel.

Diaphragm assembly for a medicament dispensing unit

A disposable medicament injector having a cylindrical barrel closed at one end by a slidable plunger and at the other end by a diaphragm assembly including a flexible wall defining a medicament chamber between the plunger and flexible wall. A needle is positioned in spaced relation to the flexible wall whereby movement of the plunger will cause the medicament to flex the flexible wall toward the needle which will then pierce the wall to establish fluid communication between the medicament chamber and the area at the other end of the needle. A finger grip is retained on the plunger end of the glass barrel by the engagement of the inner and outer surfaces of the barrel by a pair of spaced circumferential walls extending from the finger grip. A nose cap assembly is affixed to the diaphragm end of the glass barrel in a similar manner.

Disposable medicament injector

A cartridge for a prefilled hypodermic syringe of the type sealed at its forward end with a destructible diaphragm is provided with a piston-piston rod assembly in which the piston of resilient material is molded in the form of a hollow cylinder and has an auxiliary short, cup-shaped member of reduced diameter coaxially enclosed within its forward end, and sealed in yieldable engagement with the inner walls of said hollow cylinder by a transverse, annularly-shaped elastic membrane. The piston rod has a forward portion of lateral cross-section smaller than the inner cross-sectional area of the piston and slidably receivable in the latter, and a following portion having a lateral cross-section dimension greater than the inner cross-sectional area of the piston, the junction of the two rod portions forming a forwardly directed shoulder. When the piston rod is actuated, the forward reduced portion slides forwardly in the piston until it engages the auxiliary member and causes such member to distend forwardly, while the main body of the piston remains stationary. Continued actuation of the piston rod then brings the shoulder formed by the following rod portion into engagement with the main body of the piston to cause the piston to move as a whole within the syringe cartridge.

Piston construction for syringes

The attachment unit for a spike equipped syringe is composed of first and second tubular portions connected together at their inner ends and extending from such connection in axially aligned relation. The bore of the first tubular portion has at its outer end a cylindrically shaped seat for the hub of the spike, and adjacent to such cylindrical seat a conical seat for the spike, the two seats forming between them an internal shoulder to properly register the spike in such first tubular portion. Connected at its inner end to said connection and enclosed in the inner end of the second tubular portion is a tubular needle mounting, the bore of which is in communication with the bore of the first tubular portion. One end of a needle cannula is secured in liquid-tight relation in the mounting bore and the cannula extends from such mounting and through the bore of the second tubular portion to a point beyond the outer end of such second tubular portion. The projecting end of the cannula is enclosed by a cup-shaped cap which fits on the outer end of the second tubular portion and is provided with a stop flange engageable with such outer end of the second tubular portion to prevent the needle engaging the closed end of the cap.

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East Lyme, CT, United States of America

Edward A Tischlinger