Pfizer Corporation

Edward A Glazer

Michael Anthony Letavic

Takushi Kaneko

Bingwei Vera Yang

Brian S Bronk

Steven Wayne Goldstein

Hengmiao Cheng

James W McFarland

Jose R Perez

Hengmaio Cheng

Banauara L Mylari

4&Prime;-substituted-9-deoxo-9a-aza-9a homoerythromycin a derivative

Indolyl-2-phenyl bisamidines useful as antiproliferative agents

C-4&Prime;-substituted macrolide derivatives

4&Prime;-substituted-9-deoxo-9a-aza-9a-homoerythromycin a derivatives

Known bisamidine compounds are newly discovered to possess DNA methyltransferase inhibiting properties, making them useful for preparing pharmaceutical compositions useful as antiproliferative agents for treating a neoplastic or a non-neoplastic disease characterized by abnormally rapid proliferation of tissue involved in said disease; wherein said bisamidines comprise a compound of Formula (5.0.0):

Bisamidine compounds as antiproliferative agents

An antibiotic of the formula ##STR1## wherein R is hydrogen or a pharmaceutically acceptable cation and Me is methyl.

Polycyclic ether antibiotics

Variously substituted trans-3-[3-(3-hydroxypiperid-2-yl)-2-oxopropyl]quinazolin-4(3H)-ones, a method of controlling or preventing coccidiosis in poultry therewith, intermediates therefor, and a process for the preparation of certain intermediates therefor.

Quinazolin-4(3H)-one derivatives as anticoccidial agents

Variously substituted trans-3-[3-(3-hydroxypiperid-2-yl)-2-oxopropyl]quinazoline-4(3H)-ones, a method of controlling or preventing coccidiosis in poultry therewith, intermediates therefor, and a process for the preparation of certain intermediates thereof.

Certain trans-3-[3-(3-hydroxy-2-piperidyl)-2-oxopropyl]thieno[3,2-d]pyrimidin-4(3H )-one and furo[3,2-d]pyrimidin-4(3H)-one derivatives, a method of using same as anticoccidial agents, intermediates therefor, and a process for certain intermediates therefor.

Heterocyclic ring fused pyrimidine-4(3H)-ones as anticoccidial agents

Diamidines of the formula ##STR1## wherein X is a propylene, isobutylene, guanidine, pyrrole, tetrazole, imidazole or substituted imidazole group; and 2-[4-(2-imidazolinyl)phenyl]-6-(2-imidazolinyl)indole, are useful in the treatment of certain protozoal infections in mammals, particularly in cattle.

Antiprotozoal diamidines and bis-imidazoline

Heterocyclic ring fused pyrimidine-4 (3H)-ones as anticoccidial agents

Antiprotozoal 1,4-di(p-amidinophenyl)imidazoles

Antiprotozoal diamidines

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Waterford, CT, United States of America

Edward A Glazer