Acuson Corporation

Varian Medical Systems, Inc.

Siemens Medical Solutions Usa, Inc.

Cyberheart, Inc.

Edward A Gardner

Gregory L Holley

Samuel H Maslak

Patrick Maguire

John Alexander Hossack

John W Sliwa, Jr

David J Napolitano

Thilaka S Sumanaweera

Sriram Krishnan

Richard M Bennett

Michael N Woelmer

John I Jackson

Joan Carol Main

Richard Kane

Bhaskar S Ramamurthy

Jay Sterling Plugge

Mirsaid Seyed Bolorforosh

Nils Sponheim

Ting Lan Ji

Robert D Kahn

Devices, systems, and methods for planning radiosurgical treatments for neuromodulating a portion of the renovascular system may be used to plan radiosurgical neuromodulation treatments for conditions or disease associated with elevated central sympathetic drive. The renal nerves may be located and targeted at the level of the ganglion and/or at postganglionic positions, as well as preganglionic positions. Target regions include the renal plexus, celiac ganglion, the superior mesenteric ganglion, the aorticorenal ganglion and the aortic plexus. Planning of radiosurgical treatments will optionally employ a graphical representation of a blood/tissue interface adjacent these targets.

Blood-tissue surface based radiosurgical renal treatment planning

A radiosurgical method for treating cardiorenal disease of a patient, the method including directing radiosurgery radiation from outside the patient towards one or more target treatment regions encompassing sympathetic ganglia of the patient so as to inhibit the cardiorenal disease. In an exemplary embodiment, the method further includes acquiring three dimensional planning image data encompassing the first and second renal arteries, planning an ionizing radiation treatment of first and second target regions using the three dimensional planning image data so as to mitigate the hypertension, the first and second target regions encompassing neural tissue of or proximate to the first and second renal arteries, respectively, and remodeling the target regions by directing the planned radiation from outside the body toward the target regions.

Renovascular treatment device, system, and method for radiosurgically alleviating hypertension

Methods and systems are disclosed for radiating a moving object. The method may comprise acquiring a plurality of indicators of the phase of a physiological cycle of a patient and a plurality of images of the patient that include a target. Each image may be taken at a different phase of the physiological cycle and may be registered to the phase at which the image was taken. The method may also include identifying the target in each of the plurality of images, calculating a dose of radiation required to treat the target, calculating the number, orientation, and dwell time of one or more radiation beams required to deliver the calculated required dose of radiation to the target, and calculating a position of each of the one or more radiation beams required to achieve the calculated orientation. Each position may be a function of the phase of the physiological cycle to which each of the plurality of images is registered.

Radiation treatment planning and delivery for moving targets in the heart

Method and systems are disclosed for radiating a moving target inside a heart. The method includes acquiring sequential volumetric representations of an area of the heart and defining a target tissue region and/or a radiation sensitive structure region in 3D for a first of the representations. The target tissue region and/or radiation sensitive structure region are identified for another of the representations by an analysis of the area of the heart from the first representation and the other representation. Radiation beams to the target tissue region are fired in response to the identified target tissue region and/or radiation sensitive structure region from the other representation.

A target motion simulator system for use in verifying target tracking with a radiation therapy device. The system comprises a radiation detection target coupled to a first motion actuator simulating a first motion of a first tissue and a fiducial coupled to a second motion actuator simulating a second motion of a second tissue offset from the first tissue, a component of the first motion being asynchronous with the second motion. A synthetic physiological signal generator is synchronized with the component of the first motion, wherein an output signal from the generator, in combination with a sensed position of the fiducial, may be used by the radiation therapy device in tracking the target.

Test object for the validation of tracking in the presence of motion

A region of interest is identified by user selection of a single point. Multiple regions of interest may be identified by selection of multiple points. Region growing is then used to define the boundary of the region of interest.

Region of interest methods and systems for ultrasound imaging

A region of interest is identified by user selection. Multiple regions of interest may be identified. An image processing region is identified by adding additional spatial locations to a region of interest. The image processing region of interest is then used for image processing.

In one embodiment, at least one visual characteristic from a selected image is used to automatically select an ultrasound image from a set of images from a plurality of heart cycles. In another embodiment, motion correction is performed on ultrasound images that are automatically selected from a plurality of ultrasound images associated with the same phase of the heart cycle. In yet another embodiment, ultrasound images are automatically selected from a set of images based on a time interval that is within a tolerance range from a reference phase of the heart cycle. In another embodiment, a stored user-preference of a phase of the heart cycle is used to automatically select an ultrasound image from a set of images. In yet another embodiment, a user-defined region of interest is placed on an ultrasound image associated with a selected phase of a heart cycle.

Phase selection for cardiac contrast assessment

The embodiments described herein relate to a method and system for simultaneously displaying relationships of measurements of features associated with a medical image. In one embodiment, a plurality of measurements of features associated with a medical image are provided. Each of the plurality of measurements corresponds to a respective measurement type. Relationships are created between the measurements and references specific to the measurement types, and at least two of the created relationships are simultaneously displayed in a graphical display format. Examples using fetal growth data and time intensity curves are disclosed. Other embodiments are provided, and each of the embodiments described herein can be used alone or in combination with one another.

Growing community of inventors

San Jose, CA, United States of America

Edward A Gardner