Psomagen, Inc.

Ubiome, Inc.

Eduardo Morales

Zachary Apte

Jessica Richman

Daniel Almonacid

Rodrigo Ortiz

Catalina Valdivia

Inti Pedroso

Paz Tapia

Victoria Dumas

Sara W Bird

Javier Gimpel

Valeria Marquez

Ingrid Araya

Melissa Alegria

Audrey Goddard

Luis Fernando Gomez

Juan Ugalde

Janyra Espinoza

Constance Norris

Pamela Nieto

Nicolas Ordenes

Luis Leon

Paulo Covarrubias

Janet Torres

Mario Saavedra

Cristian Bravo

Natalia Scioscia

Eduardo Olivares

Felipe Sepulveda

Felipe Melis

Juan Jimenez

Embodiments of a method and/or system (e.g., for improved single molecule sequencing, etc.) can include preparing a set of unique molecular identifier (UMI)-based molecules associated with a set of target nucleic acid sequences; facilitating generation of (e.g., generating, etc.) a set of tagged nucleic acid molecules based on the set of UMI-based molecules and a set of nucleic acid molecules corresponding to (e.g., including, etc.) the set of target nucleic acid sequences; and/or facilitating (e.g., performing, etc.) single molecule sequencing with the set of tagged nucleic acid molecules.

Single molecule sequencing and unique molecular identifiers to characterize nucleic acid sequences

Therapeutic compositions and an associated method for improving a Toll-like receptor (TLR)-related condition, including determining a set of peptide sequences associated with a microorganism-related modulator of a TLR, determining a first set of binding parameters for the set of peptide sequences in relation to the TLR, selecting a target subset of peptide sequences from the set of peptide sequences based on the first set of binding parameters, reengineering the target subset of peptide sequences based on mutating amino acid residues of the target subset of peptide sequences, determining a second set of binding parameters for the reengineered target subset of peptide sequences in relation to the TLR, and identifying a first peptide for use in a therapeutic composition for improving the TLR-related condition, based on the second set of binding parameters for the reengineered target subset of peptide sequences.

Therapeutic and diagnostics compositions targeting toll-like receptors and methods thereof

Embodiments of the system and/or method can include and/or apply a magnetic device for facilitating a magnetic field for isolating the nucleic acid material from a sample, the magnetic device including a support component; and a set of magnetic pins attached to the support component and movable with at least three degrees of freedom when attached to the support component, where the set of magnetic pins provide adaptability to shapes of sample compartments of a sample container.

Method and system for high-throughput particle handling by use of magnetic fields and device

Embodiments of a method and system for improved microbiome sequencing can include: generating guide RNA complexes for a set of targets corresponding to a set of taxa associated with the microorganism-related condition; processing the biological sample with the gRNA complexes to generate microorganism nucleic acid fragments comprising a set of end regions associated with the set of targets; ligating the set of end regions with a set of adapters sharing an adapter sequence; and amplifying the set of targets based on the ligated set of end regions and a set of primers sharing a primer sequence associated with the adapter sequence.

Method and system for CRISPR-based library preparation and sequencing

Embodiments of a method and/or system can include administering, to a patient with one or more conditions associated with at least one of TMA, TMAO, and/or derivatives thereof, a therapeutically effective amount of a compound for affecting inhibiting one or more CutC enzymes and/or CntA enzymes associated with microorganisms from at least one taxon from a set of microorganism taxa.

Targeted drugs associated with trimethylamine and/or trimeihylamine-n-oxide

Embodiments of a method and/or system for characterizing an allergy-related condition for a user can include one or more of: generating a microbiome dataset for each of an aggregate set of biological samples associated with a population of subjects, based on sample processing of the biological samples; processing a supplementary dataset associated with one or more allergy-related conditions for the set of users; and performing an allergy-related characterization process for the one or more allergy-related conditions, based on the supplementary dataset and/or microbiome features extracted from the microbiome dataset.

Method and system for characterizing allergy-related conditions associated with microorganisms

Embodiments of a method and/or system for characterizing a microorganism-related condition (e.g., human behavior condition, disease-related condition, etc.) for a user can include one or more of: generating a microbiome dataset for each of an aggregate set of biological samples associated with a population of subjects, based on sample processing of the biological samples; processing a supplementary dataset associated with one or more microorganism-related conditions for the set of users; and performing a microorganism-related characterization (e.g., human behavior characterization, disease-related characterization, etc.) process for the one or more microorganism-related conditions, based on the supplementary dataset and/or microbiome features extracted from the microbiome dataset.

Method and system for characterizing microorganism-related conditions

Embodiments of a method and/or system for characterizing a diet-related condition for a user can include one or more of: generating a microbiome dataset for each of an aggregate set of biological samples associated with a population of subjects, based on sample processing of the biological samples; processing a supplementary dataset associated with one or more diet-related conditions for the set of users; and performing a diet-related characterization process for the one or more diet-related conditions, based on the supplementary dataset and/or microbiome features extracted from the microbiome dataset.

Method and system for characterizing diet-related conditions

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San Francisco, CA, United States of America

Eduardo Morales