Monsanto Technology LLC

Eduardo Aurelio Casanova

Eric A Haupfear

Henry H Chien

Peter E Rogers

Justin Robert Struble

Jian Xu

David Z Becher

David R Eaton

Stephen D Prosch

Donald D Soleta

William B Hooper

Peng Fan

Robert E Byrd

Kenneth S Meyer

James P Coleman

Juan Pedro Arhancet

Jerald D Heise

Kam-To Wan

Michael Rogers

Mark A Leiber

Lowell R Smith

Michael E Seitz

Todd Charles Friedman

John H Ahn

Junqiu Yang

William A Scholle

Amy L Jorgenson

Sunder Rangachari

Walter K Gavlick

Greg Hartmann

Mark D Scaia

Karen A Wittler, Legal Representative

John Wagenknecht

Leonard Aynardi

Oliver Lerch

Carl Mumford

Alfredo Oba

Bart Roose

Ed Ries

Randall Alberts

The present invention is generally directed to improved processes for the preparation of various phosphorus oxides and phosphoric acid. Phosphorus oxides prepared in accordance with the present invention include phosphorus (III) oxides (e.g., tetraphosphorus hexaoxide (PO)). Phosphorus (III) oxides such as POare useful products and are also useful as precursors in preparation of other products, including phosphorous acid (HPO) and other phosphorus-containing chemicals. Certain aspects of this invention are also directed to using various byproducts formed during POproduction as precursors for the formation of phosphoric acid (HPO) and PO. In particular, the present invention is directed to improved processes for the preparation of phosphorus (III) oxides (e.g., PO) suitable for use in the preparation of phospho-herbicides such N-(phosphonomethyl)glycine (glyphosate) and precursors thereof (e.g., N-(phosphonomethyl)iminodiacetic acid (PMIDA)). The present invention is thus further directed to preparation of these compounds.

Phosphorus oxide and phosphoric acid production processes

This invention relates to an improved electrodialysis method for preparing an amino acid from a salt of the amino acid utilizing a three-compartment bipolar membrane electrodialysis process wherein an aqueous electrolyte comprising an exogenous acid is added to the acid compartment of a three-compartment bipolar membrane apparatus. The exogenous acid is different than the amino acid and typically has a pKa less than the pKa of the amino acid.

Three-compartment bipolar membrane electrodialysis of salts of amino acids

This invention relates to the preparation of N-(phosphonomethyl)glycine ('glyphosate') from N-(phosphonomethyl)iminodiacetic acid ('PMIDA'), and more particularly to methods for control of the conversion of PMIDA, for the identification of reaction end points relating to PMIDA conversion and the preparation of glyphosate products having controlled PMIDA content.

Control of N-(phosphonomethyl)iminodiacetic acid conversion manufacture of glyphosate

Various processes for the separation of a mixture containing dichlorophenols are described. In various aspects, the present invention relates to separation processes that produce an extract enriched in 2,4-dichlorophenol content and an extract enriched in 2,5-dichlorophenol content. The present invention further relates to various processes that integrate with these separation processes, such as a process for producing 3,6-dichloro-2-methoxybenzoic acid (dicamba) or salt or ester thereof or a process for producing 2,4-dichlorophenoxyacetic acid (2,4-D) or salt or ester thereof.

Separation of dichlorophenols

This invention relates generally to improved methods and herbicidal glyphosate compositions for use in controlling the growth of weeds and unwanted vegetation, and particularly for use in controlling weeds in a crop of transgenic glyphosate-tolerant cotton plants by over-the-top, foliar application of a herbicidal glyphosate formulation.

Mitigating necrosis in transgenic glyphosate-tolerant cotton plants treated with herbicidal glyphosate formulations

Control of N-(phosphonomethyl)iminodiacetic acid conversion in manufacture of glyphosate

Processes for the preparation, concentration and recovery an N-(phosphonomethyl)glycine product from aqueous process streams including contacting mother liquor generated in the precipitation of N-(phosphonomethyl)glycine product crystals with a selective membrane to produce a retentate enriched N-(phosphonomethyl)glycine product and a permeate depleted in N-(phosphonomethyl)glycine product are disclosed.

Process for selective removal of water and impurities from N-(phosphonomethyl)glycine

An improved process for recovering a crystalline product (particularly an N-(phosphonomethyl)glycine product) from a solution comprising both a product subject to crystallization and undesired impurities is provided.

Process for recovering a crystalline product from solution

This invention generally relates to liquid phase oxidation processes for making N-(phosphonomethyl)glycine (also known in the agricultural chemical industry as glyphosate) and related compounds. This invention, for example, particularly relates to processes wherein an N-(phosphonomethyl)iminodiacetic acid (NPMIDA) substrate (i.e., N-(phosphonomethyl)iminodiacetic acid, a salt of N-(phosphonomethyl)iminodiacetic acid, or an ester of N-(phosphonomethyl)iminodiacetic acid) is continuously oxidized to form an N-(phosphonomethyl)glycine product (i.e., N-(phosphonomethyl)glycine, a salt of N-(phosphonomethyl)glycine, or an ester of N-(phosphonomethyl)glycine). This invention also, for example, particularly relates to processes wherein an N-(phosphonomethyl)iminodiacetic acid substrate is oxidized to form an N-(phosphonomethyl)glycine product, which, in turn, is crystallized (at least in part) in an adiabatic crystallizer.

Reaction systems for making N-(phosphonomethyl) glycine compounds

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University City, MO, United States of America

Eduardo Aurelio Casanova