Sanofi-aventis

Sanofi

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Sandor Batori

Tibor Szabo

Zoltan Kapui

Peter Aranyi

Katalin Urban-Szabo

Marton Varga

Lajos T Nagy

Philippe Bovy

Imre Bata

Eva Boronkay

Laszlo Balazs

Karoly Kanai

Endre Mikus

Judit Vargane Szeredi

Kinga Boer

Geza Timari

Michel Finet

Veronika Bartane Bodor

Zoltán Kapui

Katalin Urban Szabo

Agnes Pappne Behr

Mihalyne Santa, Legal Representative

Marianna Kovacs

Márton Varga

Sándor Batori

Péter Aranyi

Lászlo Balazs

The present invention relates to the adenosine Areceptor ligands of the general formula (I), within them favourably to the antagonists, to their salts, solvates, N-oxides and isomers, to the pharmaceutical compositions containing the compounds of the general formula (I), their salts, solvates, N-oxides and isomers, to the use of the compounds of the general formula (I), their salts, solvates, N-oxides and isomers, to the preparation of the compounds of the general formula (I), their salts, solvates, N-oxides and isomers, as well as to the new intermediates of the general formula (II), (VI), (XI), (XII) and (XV), and to the preparation thereof.

Compounds

The present invention relates to new, potent DPP-IV enzyme inhibitors of the general formula (I), which contain fluorine atoms.

Fluoropyrrolidines having dipeptidyl peptidase enzyme inhibitory activity

The invention relates to a compound of the general formula (I), as defined herein which is useful for the treatment of a pathology in a patient wherein a CCR3 receptor plays a role in the development of the pathology, and pharmaceutical preparations containing such compound. The invention is also directed to a process for preparing the compound of the general formula (I), and intermediate useful in the preparation.

Amino-alkyl amide derivatives as CCR3 receptor ligands

The present invention relates to the novel compounds of the general formula (I) possessing dipeptidyl peptidase IV enzyme inhibitory activity, pharmaceutical compositions thereof, methods of using said compounds, processes for their preparation and intermediates of the general formulae (II), (IV), (V), (VII), (VIII) and (IX).

Compounds useful for DPP-IV enzyme inhibition

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Dunakeszi, Hungary

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