Richter Gedeon Vegyeszeti Gyar Rt

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Laszlo Tardos

Endre Kasztreiner

Istvan Elekes

Sandor Elek

Gyorgy Cseh

Laszlo Jaszlits

Istvan Polgari

Geza Szilagyi

Judit Kosary

Peter Matyus

Zsuzsa Huszti

Agnes Kenessey

Pal Tolnay

Janos Borvendeg

Laszlo Nagy

Zsuzsanna Huszti

Gabriella Kiss

Erzsebet Szuucs

Andras Divald

Ilona Kovacs, Nee Szabo

Szilagyi Geza

Pyridazinylhydrazones capable of lowering blood pressure have the formula ##STR1## wherein R.sup.1 is hydrogen, chlorine, alkyl having from 1 to 4 carbon atoms, methoxy, hydroxyl, carbamoyl or cyano;

Novel pyridazinylhydrazones and method of administering same

A pharmaceutical compositions with hypotensive effects which comprise a compound of formula (I) or a pharmaceutically acceptable acid addition salt thereof, ##STR1## wherein R.sup.1 is formula (II) ##STR2## wherein R.sup.4 and R.sup.5 each represent hydrogen, hydroxy, nitro at the same time

Compositions with potentiated hypotensive effects

Pyridazinylhydrazones capable of lowering blood pressure having the formula ##STR1## wherein R.sup.1 is hydrogen, chlorine, alkyl having from 1 to 4 carbon atoms, methoxy, hydroxyl, carbamoyl or cyano;

Morpholino pyridazinylhydrazones

3-(1-Pyrazolyl)-pyridazine derivatives of the formula I, or pharmaceutically acceptable acid addition salts thereof, which decrease high blood pressure and inhibit catabolism or prostaglandins, ##STR1## wherein R.sup.1 is hydrogen or C.sub.1-4 alkyl,

3-(1-Pyrazolyl)-pyridazine derivatives

The invention relates to compounds of general formula ##STR1## wherein R.sup.1 stands for a hydrogen atom or a C.sub.1-6 alkyl-, a C.sub.2-4 hydroxyalkyl, a C.sub.3-6 cycloalkyl or a phenyl group,

3-(1-Pyrazolyl)-pyridazine derivatives and hypotensive compositions

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Budapest, Hungary

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