Smith + Nephew

Aap Biomaterials Gmbh & Co. Kg

Edgar Wüst

Helmut Wahlig

Elvira Dingeldein

Christoph Sattig

Jörg Bauer

System of implant components containing active agents, wherein each component is intended to function as an additive for an implant material produced with a powdery or finely granulated starting material and/or active agents and additives. Each component is powdery or finely granulated and includes at least one powdery or finely granulated active agent or additive having a higher dosage than the desired concentration for the application. The components themselves are made of a powdery or finely granulated starting material for the implant material, as well as of the active agent or additive. The active agents can be chemotherapeutical agents, such as antibiotics, whereas the additives can be x-ray contrast materials and/or or additives that alter the physical properties of the starting material, such as its elasticity or viscosity.

Modular implant system containing active substances and method for the production thereof

Blister packaging unit () for at least two components packed in separate individual packages, at least one of which has a pulverulent or granular consistency, which are to be prepared before use with the further packaged component(s) in a mixer or applicator to form a ready-to-use mixture. The individual packages of the components are inserted in correspondingly pre-shaped receptacles () in the blister () of a suitable film or other material and this blister is closed on the side of the open mouth of the receptacles by a cover () of cardboard, plastic, metal or some other suitable material which may be torn off or opened in some other manner. The component(s) having the pulverulent or granular consistency is/are packaged in a respective individual blister pack () shaped at least approximately complementarily to the associated receptacle () in the blister packaging unit, the blister of which has the shape of an elongate trough element () of plastic material tapered at at least one end in the manner of a spout, which trough element(s) comprises a separate tear-off cover () of cardboard, plastic, metal or some other suitable material which may be torn off or opened in some other manner.

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Rodgau, Germany

Edgar Wüst