Gen-probe, Inc.

Quest Diagnostics Investments, Inc.

Dendreon Corporation

The Burnham Institute

Deadreon Corporation

Dendreon San Diego LLC

Edgar Ong

Edwin L Madison

Maurice Exner

Jeffrey M Linnen

Kui Gao

Jennifer Cole

James John Hogan

Michael R Reshatoff

Joseph Edward Semple

Gian Luca Araldi

Jiunn-chern Yeh

John Eugene Reiner

Gary Samuel Coombs

Minoru Fukuda

Disclosed is a method for determining the presence ofcomplex nucleic acids in a biological sample. In particular, the mig gene ofand the DT1 gene ofare detected, preferably following amplification. In addition, the method distinguishes between species ofand. Also described are oligonucleotides that can be used as primers to amplify target genes such as mig and DT1 genes and as probes as well as kits containing the oligonucleotide.

Kits for detectingnucleic acid

Disclosed are nucleic acid oligomers, including amplification oligomers, capture probes, and detection probes, for detection of Hepatitis E Virus (HEV) nucleic acid. Also disclosed are methods of specific nucleic acid amplification and detection using the disclosed oligomers, as well as corresponding reaction mixtures and kits.

Compositions and methods for detecting HEV nucleic acid

Provided are compositions, kits, and methods for the identification ofIn certain aspects and embodiments, the compositions, kits, and methods may provide improvements in relation to specificity, sensitivity, and speed of detection.

Compositions, kits and related methods for the detection and/or monitoring of salmonella

Provided are compositions, kits, and methods for the identification of. In certain aspects and embodiments, the compositions, kits, and methods may provide improvements in relation to specificity, sensitivity, and speed of detection.

[object Object]

Disclosed is a method for determining the presence ofcomplex nucleic acids in a biological sample. In particular, the IS1245 gene ofand the DT1 gene ofare detected, preferably following amplification. In addition, the method distinguishes between species ofand. Also described are oligonucleotides that can be used as primers to amplify target genes such as IS1245 and DT1 genes and as probes as well as kits containing the oligonucleotides.

Provided herein is are polypeptides that include the protease domain of a type II transmembrane serine protease (MTSP) as a single chain. Methods using the polypeptides to identify compounds that modulate the protease activity of an MTSP are provided. Also provided are MTSPs designated MTSP3 and MTSP4 and a form of an MTSP designated MTSP6.

Nucleic acid molecules encoding transmembrane serine proteases, the encoded proteins and methods based thereon

Disclosed is a method for determining the presence ofcomplex nucleic acids in a biological sample. In particular, the mig gene ofand the DT1 gene ofare detected, preferably following amplification. In addition, the method distinguishes between species ofand. Also described are oligonucleotides that can be used as primers to amplify target genes such as mig and DT1 genes and as probes as well as kits containing the oligonucleotides.

Provided herein are endotheliases and portions, particularly, the protease domains, and nucleic acids that encode the endotheliases. The endotheliases are transmembrane proteases expressed in endothelial cells. The nucleic acids and encoded proteins and protease domain portions thereof are used in a variety of prognostic, diagnostic, therapeutic and screening methods, including methods for screening for compounds that modulate angiogenesis.

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San Diego, CA, United States of America

Edgar Ong