W. L. Gore & Associates, Inc.

Other

Edgar G Ashmead

Edward C Gunzel

Michael Moritz

Chris Cullen

Michael P Moritz

A container having a barrier layer is provided. The container may be of thermoplastic and the barrier may inhibit materials from leaching from the thermoplastic material or from extraction of compounds from medicants by the thermoplastic. A process is also described that allows for molding thin barrier layers as container lines and for forming thermoplastic containers with barrier liners.

Fluoropolymer barrier material for containers

A valve-coupler system has a lever that extends under a length axis of the valve body to enable one-handed operation. The valve-coupler body has an opening that is configured over a valve stem and a seal actuator having a lever that can be rotated about a pivot with a single hand to create a seal around the valve stem. Additionally, a valve-coupler may have a gas inlet valve that can be activated by the same single hand to open the valve and allow gas to flow into the valve stem. The inlet valve may be configured in line with the lever whereby the inlet valve is opened when the lever is rotated about the pivot to contact the inlet valve. The inlet valve may be configured on the valve body for manipulation by a user's finger or thumb. The inlet valve may be on the top of the valve body.

Valve-coupler actuating system

A pre-filled syringe having containing therein at least one therapeutic is provided. The syringe contains a silicone free barrel and an elastomeric syringe stopper that is covered with an expanded polytetrafluoroethylene barrier layer. The presence of a barrier layer that is at least partially porous on the outside of the syringe stopper improves the seal between the stopper and syringe barrel and minimizes the sliding force. In some embodiments, the barrel is formed of a glass material such as a borosilicate glass, that is free of silicone or other lubricants.

Silicone free drug delivery devices

Fluoropolymer barrier materials for containers

A syringe stopper that is suitable for use in syringes without silicone oil or other liquid lubricants. The invention provides a low friction barrier between an elastomeric stopper material and a therapeutic in the syringe. The barrier may inhibit materials from leaching from the elastomer material or from extraction of compounds from medicants by the elastomer. A process is also described that allows for molding thin barrier layers while allowing adequate bonding with the elastomer.

Growing community of inventors

Lincoln University, PA, United States of America

Edgar G Ashmead