Northeastern University

Edgar Daniel Goluch

Slava Epstein

Yoshiteru Aoi

Thaddaeus A Webster

Hunter J Sismaet

Nanofluidic devices and methods of the invention are capable of autonomously isolating individual microbial cells using constrictive channels and growing monocultures of the cells for automated characterization of their biochemical properties and interactions with mammalian cells. Single microbial cells, such as bacterial cells, are isolated directly from environmental sources and cultured using chemical factors from their native environment.

Nanofluidic device for isolating, growing, and characterizing microbial cells

Methods and devices for monitoring the viability of a biofilm comprisingbacteria are provided by detecting pyocyanin. The invention relates to electrochemical methods and devices that offer a simple and inexpensive alternative for immediate identification of bacterial infection due to the presence of. In some embodiments, an inexpensive, disposable electrochemical sensor can be used to rapidly screen for the presence ofin clinical wound effluent samples.

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Boston, MA, United States of America

Edgar Daniel Goluch