Brigham Young University

Perkinelmer Health Sciences, Inc.

Leco Corporation

Sensar, Inc.

Edgar D Lee

Milton L Lee

Alan L Rockwood

Randall W Waite

Nathan L Porter

Samuel E Tolley

Stephen A Lammert

Jeffrey L Jones

Aaron Roe Hawkins

Larry J Davis

Anthony David Rands

H Dennis Tolley

James Oliphant

Daniel E Austin

Bingfang Yue

Randal W Waite

Kent Johnson

Dan Patten

Dan Haab

Nosa Agbonkonkon

Li Zhou

Richard Rollins

A system and method for performing field-portable GC/MS measurements for the rapid sampling and measurement of high temperature boiling semi-volatile organic compounds in environmental samples, wherein other column bundles have cold spots that may prevent high temperature boiling semi-volatile components from eluting the GC column, this new design may eliminate those cold spots on the GC column.

Low thermal mass GC module

Certain configurations described herein are directed to gas chromatography devices. In some instances, the gas chromatography devices may comprise at least one heating device which can be moved along a chromatography column to provide a thermal gradient to the chromatography column. In other instances, the gas chromatography devices may comprise a heating device that can receive a moving chromatography column to provide a thermal gradient to the chromatography column. The gas chromatography devices may be configured as portable devices which can be used to perform remote analyses.

Thermal gradient chromatography devices and methods of using them

Certain configurations described herein are directed to gas chromatography devices. In some instances, the gas chromatography devices may comprise at least one heating device which can be moved along a chromatography column to provide a thermal gradient to the chromatography column. In other instances, the gas chromatography devices may comprise a heating device that can receive a moving chromatography column to provide a thermal gradient to the chromatography column. The gas chromatography devices may be configured as portable devices which can be used to perform remote analyzes.

A scaled down version of a toroidal radio frequency (RF) ion trap mass analyzer operating with RF trapping voltages on the order of 1 kVyet despite the reduced dimensions, retains roughly the same ion trapping volume as conventional 3D quadrupole ion traps, wherein the curved geometry enables construction of a compact mass analyzer and easy interface with conventional electron multipliers.

Miniature toroidal radio frequency ion trap mass analyzer

A coaxial hybrid ion trap that uses two substantially planar opposing plates to generate electrical focusing fields that simultaneously generate at least two different types or shapes of trapping regions, wherein a first trapping region is a quadrupole trapping region disposed coaxially with respect to the opposing plates, and wherein a second trapping region is a toroidal ion trap having a toroidal trapping region that is simultaneously created around the quadrupole trapping region.

Coaxial hybrid radio frequency ion trap mass analyzer

A virtual ion trap that uses electric focusing fields instead of machined metal electrodes that normally surround the trapping volume, wherein two opposing surfaces include a plurality of uniquely designed and coated electrodes, and wherein the electrodes can be disposed on the two opposing surfaces using plating techniques that enable much higher tolerances to be met than existing machining techniques.

Virtual ion trap

A cross-flow ion mobility analyzer (CIMA) that includes a component of gas flow that opposes an electric field that is established within a channel, wherein ions are carried through the channel, wherein ions of a specific mobility are trapped by the opposing electric field and flow field within the channel and are detected when the ions reach the end of the channel, wherein a detector at the end of the channel sees a continuous stream of mobility-selected ions, and wherein different ions are selected by modifying the electric field and/or the velocity of the flow field.

Cross-flow ion mobility analyzer

A single set of electrodes, wherein different electrical potentials are applied to the single set of electrodes at different times in order to perform both ion mobility-based spectrometry and mass spectrometry (MS) on a sample of ions, wherein the ions are processed by performing ion mobility-based spectrometry and mass spectrometry in any sequence, any number of times, and as isolated or superposed procedures in order to trap, separate, fragment, and/or analyze charged particles and charged particles derived from atoms, molecules, particles, sub-atomic particles and ions.

Single device for ion mobility and ion trap mass spectrometry

A system and method are provided of extracting spectra from data produced by temporally indexed spectral scans from a spectrometer and spectrometer. The method includes the operation of receiving a data matrix from the spectrometer. The noise can then be removed from the data matrix. A further operation is identifying spectra of interest in the data matrix based on information content. In addition, a reduction transformation can be applied to the data matrix based upon the spectra of interest based upon the denizen transformation for the purpose of extracting the spectra of interest from the data matrix.

System and method for extracting spectra from data produced by a spectrometer

A radio-frequency quadrupole ion guide having a symmetrical magnetic field disposed along an axis of the ion guide, wherein the system provides prolonged interaction between electrons and uncharged compounds within an ionization volume of the ion guide, resulting in enhanced ion creation.

Electron ionization source for othogonal acceleration time-of-flight mass spectrometry

A method and apparatus for focusing ions for delivery to an ion detection device using an aerodynamic ion focusing system that uses a high-velocity converging gas flow at an entrance aperture to focus an ion plume by reducing spreading and increasing desolvation of ions, and wherein a voltage is applied to at least a portion of the aerodynamic ion focusing system to assist in the focusing and delivery of ions to the ion detection device.

Method and apparatus for aerodynamic ion focusing

The present invention is embodied in a method and apparatus for utilizing inherently insulative material, such as the glass and epoxy resins used in construction of printed circuit boards, for construction of components in a time of flight mass spectrometer. By using printed circuit board materials, the present invention can take advantage of fabrication techniques for providing circuit traces on surfaces, from one side to another as a via, or embedded within the printed circuit material so as to be covered except where necessary to be exposed to make contact with other electrical devices. Embedded circuit traces also enable capacitive coupling to AC energy while maintaining electrical and physical isolation. Consequently, the present invention enables both invasive and non-invasive access to pressure and vacuum chambers.

Printed circuit boards as insulated components for a time of flight mass spectrometer

A high speed data acquisition system which acquires an analog signal, converts it to digital data, and compresses the large volume of accumulated data into a format that can be handled in a microcomputer environment. The data acquisition system of the present invention can rapidly and continuously acquire and process large volumes of data. Included is an averaging circuit which allows the present invention to efficiently process and store large amounts of data uninterruptedly. The present invention is thus well suited for applications that require uninterrupted high-speed sampling over long periods of time.

Growing community of inventors

Highland, UT, United States of America

Edgar D Lee