Roche Diagnostics Operations, Inc.

Boehringer Mannheim Gmbh

Roche Diabetes Care, Inc.

Roche Diagnostics Gmbh

F. Hoffmann-La Roche Ag

Edgar Baumann

Karl Miltner

Karl Werner

Frederic Wehowski

Kai-Oliver Schwenker

Stefan Kalveram

Wolfgang Heck

Gertrud Albrecht

Markus Serr

Manfred Seidenstricker

Wolfgang Obermeier

Christian Niesporek

Klaus Wettengel

Konstanze Bogumil

Markus Genthner-Riegler

Wolgang Heck

Frédéric Wehowski

Methods, analytical devices and analytical systems are provided for determining at least one analyte concentration in a body fluid sample. The methods, which may be incorporated into the devices and systems, can include the following steps: applying a body fluid to a test carrier; illuminating the test carrier by at least one light source, where the at least one light source is modulated by using at least two modulation frequencies; receiving light remitted by the test carrier by using at least one detector; determining an analyte concentration by evaluating at least one detector signal generated by the detector, where the detector signal is demodulated with the at least two modulation frequencies to generate at least two demodulated detector signals, each demodulated signal corresponding to one of the modulation frequencies; and detecting a fault by comparing the at least two demodulated detector signals.

Methods of determining an analyte concentration in a body fluid sample, as well as analytical devices and systems for use therein

A test tape for analyzing body fluids is provided comprising a flexible carrier tape and a plurality of test fields arranged spaced apart thereon for the detection of an analyte in the body fluid. The carrier tape is provided with indicator areas to register the distance and/or determine the position of the test tape or its components during tape transport.

Test tape and analytical system

Method of detecting and evaluating analog photometric signals in a test carrier analysis system, and apparatus for carrying out the method. The test field of a test carrier is irradiated by a light source clocked in light-dark phases. The reflected light is detected by a measurement receiver over a measurement period having several light-dark phases, and integrated. An effective suppression of stray and secondary light, which permits measurement even without the hitherto conventional shielding from ambient light, is achieved by a method in which the sequence of the light and dark phases integrated over the measurement period is irregular in such a way that the Fourier-transformed frequency spectrum includes a large number of different frequencies. Each individual frequency therefore makes only a small contribution to the measurement result.

Light source pulsed with irregular pulse sequence in analog photometric

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Mannheim, Germany

Edgar Baumann