Cytrx Corporation

Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt.

Biorex Kutato Es Fejleszto Rt

Biorex Research & Development Co.

Biorex Kutato Es Fejleszo Rt.

Ede Márványos

László Ürögdi

László Dénes

Magdolna Bathóné Török

Zita Jegesné Csákai

Dezso Korbonits

Pal Kiss

Gergely Heja

Endre Palosi

Ida Szvoboda Nee Kanzel

Csaba Gonczi

Maria Szomor Nee Wundele

Judit Kun

Andrea Jednakovits

Mihaly Barabas

Gábor Balogh

Laszlo Jaszlits

Ibolya Horváth

Katalin Biro

Karoly Horvath

Péter Literáti Nagy

Zsolt Török

Mária Kürthy

László Vígh

Vera Kovacs Nee Mindler

Andrea Jednákovits

Attila Glatz

Beatrix Farkas

Katalin Bíró

György Dormán

László Korányi

Livia Nagy Nee Koranyi

László Jaszlits

Mihály Barabás

Erzsébet Hegedüs

Éva Udvardy

Dénes Medzihradszky

Bea Mézes

Eszter Kovács

Gabor T Szabo

Tamas U Kallay

Laszlo Vereczkey

Laszlo Ledniczky

Gyorgy Dorman

Erzsebet Radvanyi Nee Hegedus

Jenö Szilbereky

Istvanne Udvardy Nagy

Istvanne Udvardy-Nagy

Magdolna Torok

Erzsebet Radvanyne

Ernö Duda

Jenó Szilbereky

Ernó Duda

Sandor Erdo

Erno Bacsy

Marta Vitai

Gyorgy Schmidt

Marta Sinka

A method of increasing expression of a molecular chaperon by a cell and/or enhancing the activity of a molecular chaperon in cells is provided. The method comprises treating a cell that is exposed to a physiological stress which induces expression of a molecular chaperon by the cell with an effective amount of a certain hydroxylamine derivative to increase the stress. Alternatively, an hydroxylamine derivative can be administrated to a cell before it is exposed to a physiological stress which induces expression of a molecular chaperon by the cell. Preferably, the cell to which an hydroxylamine derivative is administered is an eukaryotic cell. The hydroxylamine derivative corresponds to the formulae (I) or (II). The invention also provides novel hydroxylamine derivatives falling within the scope of the formulae (I) and (II) as well as pharmaceutical and/or cosmetical compositions comprising the said compounds.

Method of enhancing cellular production of molecular chaperone, hydroxylamine derivatives useful for enhancing the chaperone production and the preparation thereof

The subject invention relates to carboxamidine derivatives, to pharmaceutical compositions comprising the same, and the use thereof in the preparation of pharmaceutical compositions for the treatment of vascular diseases.

Carboxamidine derivatives and their use in the treatment of vascular diseases

The subject invention relates to carboxamidine derivatives, to pharmaceutical compositions containing the carboxamidine derivatives of the invention, and the use thereof for the treatment of vascular diseases and in the preparation of pharmaceutical compositions for the treatment of vascular diseases.

Pharmaceutically effective compounds

The invention relates to carboxamidine derivatives to pharmaceutical compositions containing the same and the use thereof in the preparation of pharmaceutical compositions for the treatment of vascular diseases.

Method of enhancing cellular production of molecular chaperon, hydroxylamine derivatives useful for enhancing the chaperon production and the preparation thereof

Pharmaceutical products for curing and preventing illnesses connected

Anti-ischaemic hydroxylamine derivatives and pharmaceutical compositions

Hydroximic acid derivatives, pharmaceutical compositions containing

The invention relates to a process for the preparation of compounds of formula (I) ##STR1## wherein R.sup.1 stands for hydrogen or the group COR.sup.2, wherein

Process for the preparation of diphenyl ether derivatives

A process is disclosed for the preparation of a compound of the formula (XI) ##STR1## or a salt thereof, wherein R.sup.1 is hydrogen, halogen, C.sub.1 to C.sub.4 alkyl, C.sub.1 to C.sub.3 alkoxy, or trifluoromethyl;

Process for the preparation of 5(6)-thio substituted benzimidazoles

A new process is disclosed for the preparation of a compound of the formula (VIII) ##STR1## wherein R.sup.1 is hydrogen, halogen, C.sub.1-4 alkyl, C.sub.1-3 alkoxy, or trifluoromethyl;

Production of thiocyanato benzimidazoles

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Budapest, Hungary

Ede Márványos