Bruker Biospin Gmbh

Broker Biospin Gmbh

Eckhard Bez

Werner E Maas

Michael Fey

Kimberly Colson

Brian Marquez

Robert Krull

Don Piroli

Melanie Rosay

Yit Aun Lim

Xiaozhong Zhang

Leo Tometich

A monitoring cell, used to perform a measurement in an NMR spectrometer of a reaction fluid produced by a reaction vessel, has a body having inlet and outlet transport coaxial capillaries for transporting the reaction fluid between the body and the reaction vessel. Cooling lines are also positioned coaxially with the transport capillaries to transport cooling liquid between the body and the reaction vessel. The cell further has a hollow sample probe for insertion into the NMR spectrometer and a coupler section that removably connects the sample probe to the body so that the inlet transport capillary extends through the body into the interior of the sample probe and the outlet transport capillary is sealed to the sample probe to allow reaction fluid that enters the sample probe via the inlet transport capillary to exit the sample probe via the outlet transport capillary.

NMR reaction monitoring flow cell

Each NMR rotor bearing in an NMR magic angle spinning assembly is constructed of a porous ceramic material and has no inlet channels or nozzles. Instead, pressurized gas is forced through pores in the bearing ceramic material from an annular groove at the bearing periphery to the central aperture. Since the pores are small and very numerous, the gas pressure is effectively balanced around the periphery of the central aperture. In addition, if contaminants block one or more pores during operation, the pores are so numerous that the balanced pressure can still be maintained in the central aperture, thereby preventing an imbalance that could destroy the rotor.

NMR MAS rotor assembly with porous ceramic bearings

A closed container having a single opening is sealed by a plug fabricated from a self-sealing elastomer. Before insertion, the plug is transfixed with a tube to allow air to escape as the plug is pushed into the container. The plug and tube are then inserted into a container. After the plug has been seated in the container, the tube is withdrawn, allowing the self-sealing elastomeric material to close the canal formed by the tube and to form a hermetic seal.

Adaptive closure with removable vent for sealing containers and method of use

In a nuclear magnetic resonance probe, the sample coil is connected to the RF excitation source via transmission lines that are arranged to generate one or more nodal points at theH excitation frequency along their lengths and a balanced magnetic filed profile within the sample coil. Heat exchangers are then connected directly to the inner conductor of the transmission line at these nodal points. The transmission line inner conductors are in direct contact with the sample coil and efficiently cool the coil to cryogenic temperatures without interfering with theH resonance or RF profile.

Nuclear magnetic resonance probe with cooled sample coil

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Littleton, MA, United States of America

Eckhard Bez