Cassella Aktiengesellschaft

Cassella Aktiengellschaft

Eckard Kujath

Karl Schonafinger

Melitta Just

Rudi Beyerle

Helmut Bohn

Manfred Schrod

Jorg Ostrowski

Christian Baumgartner

Gerhard Zoller

Wolfgang Bauer

Klaus Delpy

SchoKarl

Dieter Voegele

Wolfgang Rybczynski

Method of preparing 1-amino-2, 6-dimethylpiperidine

The present invention relates to 3-(cis-2,6-dimethylpiperidino)sydnone imine salts of the general formula I ##STR1## in which X denotes H.sub.2 PO.sub.4 or ##STR2## processes for their preparation and their use.

Salts of 3-(cis-2,6-dimethylpiperidino) sydnone imine

The present invention relates to a process for the preparation of pyrrole derivatives of the general formula I ##STR1## by reaction of a compound of the general formula III ##STR2## where R, R.sup.1 and R.sup.2 are defined as specified in claim 1, in a Vilsmeier reaction. The reaction is carried out in an easily degradable solvent, the reaction product is isolated with the aid of a water-miscible extractant and is purified by high-vacuum distillation in the short path evaporator.

Process for the preparation of pyrrole derivates

Substituted 3-aminosydnone imines of the formula I ##STR1## and their pharmacologically acceptable acid addition salts, in which R.sup.1 denotes e.g. hydrogen;

Substituted 3-aminosydnone imines

Substituted 3-aminosydnone imines of the general formula I ##STR1## and their pharmacologically acceptable acid addition salts, in which A denotes an alkylene chain;

Substituted 3-aminosydnone imines, pharmaceutical compositions

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Maintal, Germany

Eckard Kujath