University of Washington

Washington Research Foundation

Other

Zymogenetics, Inc.

Holly, Julie Ann

Parker, Gary E.

Earl W Davie

Donald C Foster

Kotoku Kurachi

Savio L Woo

Chandra Thirumalachary

Gary E Parker

Julie Ann Holly

Akitada Ichinose

Ronald L Seale

Genomic and cDNA sequences coding for a protein having substantially the same biological activity as human protein C are disclosed. Recombinant plasmids and bacteriophage transfer vectors incorporating these sequences are also disclosed.

DNA sequence coding for protein C

DNA sequences to mammalian .alpha..sub.1 -antitrypsin are provided which can be used for expression of mammalian .alpha..sub.1 -antitrypsin. This work was supported in part by grants HL16919 and HL27509 from the National Institutes of Health.

DNA sequences expressing mammalian .alpha..sub.1 -antitrypsin

DNA sequences expressing mammalian .alpha..sub.1 antitrypsin

DNA sequences to mammalian .alpha..sub.1 -antitrypsin are provided which can be used for expression of mammalian .alpha..sub.1 -antitrypsin.

DNA sequences expressing mammalian alpha-1-antitrypsin

Plasmid coding for human protein C

There is disclosed an isolated DNA sequence and the amino acid sequence for human factor IX. The isolated DNA sequence and its flanking sequences are useful for determining mutations, deletions or other modifications in genetic sequences expressing normal factor IX or modifications thereof.

DNA preparation of Christmas factor and use of DNA sequences

Growing community of inventors

Bellevue, WA, United States of America

Earl W Davie