Advanced Cardiovascular Systems, Inc.

Abbott Cardiovascular Systems, Inc.

Arrow International Limited

Vasonova, Inc.

E Tina Cheng

Stephen D Ainsworth

James M Jacobs

Bradley B Hill

Sorin Grunwald

Wilfred J Samson

Fiona Maria Sander

James K Hong

Santosh V Prabhu

Diem Uyen Ta

Carla Rosa Pienknagura

Napoleon L Caliguiran

Kyle Marie Krueger

Sharon Segvich

Timothy A Limon

Daniel L Cox

Orlando M Padilla

Rosabel Chang

Suzanne Wallace George

An endovascular navigation system and method are disclosed. The endovascular navigation system includes an elongate flexible member, a processor, and a display. The elongate flexible member includes an endovascular electrogram lead disposed at its distal end for sensing an endovascular electrogram signal of the venous vasculature of the patient, and a first wireless interface configured to wirelessly transmit the endovascular electrogram signal to the processor. The processor includes a second wireless interface configured to wirelessly receive the endovascular electrogram signal from the elongate flexible member. The processor is configured to determine that the position of the distal end of the elongate flexible member is within a predetermined structure within the venous vasculature of the patient. The display is configured to display a visual indication that the distal end of the elongate flexible member is within the predetermined structure.

Apparatus and method for endovascular device guiding and positioning using physiological parameters

An endovascular navigation system and method are disclosed. The endovascular navigation system includes an elongate flexible member, a endovascular electrogram lead disposed at a distal end of the elongate flexible member and configured to sense an endovascular electrogram signal, a processor and an output device. The processor is configured to receive the endovascular electrogram signal, to determine a peak amplitude of a P-wave in the endovascular electrogram signal, and to determine that the position of the distal end of the elongate flexible member is within a predetermined structure within the venous vasculature of the patient. The output device is configured to display a visual indication that the distal end of the elongate flexible member is within the predetermined structure within the venous vasculature of the patient, where the visual indication is different from the endovascular electrogram signal of the venous vasculature of the patient.

The invention is directed to an expandable stent for implanting in a body lumen, such as a coronary artery, peripheral artery, or other body lumen. The invention provides for a an intravascular stent having a plurality of cylindrical rings connected by undulating links. The stent has a high degree of flexibility in the longitudinal direction, yet has adequate vessel wall coverage and radial strength sufficient to hold open an artery or other body lumen.

Intravascular stent

The present invention is directed to a flexible expandable stent for implantation in a body lumen, such as a coronary artery. The stent generally includes a series of metallic cylindrical rings longitudinally aligned on a common axis of the stent and interconnected by a series of links which be polymeric or metallic. Varying configurations and patterns of the links and rings provides longitudinal and flexural flexibility to the stent while maintaining sufficient column strength to space the cylindrical rings along the longitudinal axis and providing a low crimp profile, enhanced stent security and radial stiffness.

Flexible stent

A method for evaluating flow characteristics in a vessel of a patient includes the steps of positioning a catheter having a balloon at a measuring location within the vessel; transmitting an ultrasound signal into the vessel while the balloon catheter is within the measuring location; evaluating a reflection of the ultrasound signal to determine a flow parameter within the vessel while the catheter is in the measuring position; expanding the balloon within the vessel at the measuring location; and stopping the expanding step when the result of the evaluating step is that the flow through the vessel is substantially stopped. In some embodiments, the method may further comprise the step of detecting an endovascular electrogram signal. The method may be designed for evaluating flow characteristics in a vessel of a patient while enabling the prevention of a balloon from over-expanding and/or over-distending a vessel of a patient.

Endovascular devices and methods of use

An endovascular access and guidance system has an elongate body with a proximal end and a distal end; a non-imaging ultrasound transducer on the elongate body configured to provide in vivo non-image based ultrasound information of the vasculature of the patient; an endovascular electrogram lead on the elongate body in a position that, when the elongate body is in the vasculature, the endovascular electrogram lead electrical sensing segment provides an in vivo electrogram signal of the patient; a processor configured to receive and process a signal from the non-imaging ultrasound transducer and a signal from the endovascular electrogram lead; and an output device configured to display a result of information processed by the processor.

The invention is directed to an expandable stent for implantating in a body lumen, such as a coronary artery, peripheral artery, or other body lumen. The invention provides for a an intravascular stent having a plurality of cylindrical rings connected by undulating links. The stent has a high degree of flexibility in the longitudinal direction, yet has adequate vessel wall coverage and radial strength sufficient to hold open an artery or other body lumen.

Patterns for polymeric radially expandable implantable medical devices such as stents for implantation into a bodily lumen are disclosed. Some patterns comprise radially expandable cylindrical rings that are longitudinally aligned, each ring comprising diamond-shaped elements, each formed by four linear bar arms. The patterns con also comprise a cross-like element comprising four linear bar arms interconnected within the diamond-shaped elements, and at least one link between adjacent rings. In other patterns, the rings comprise peaks and valleys formed by linear bar arms. wherein pairs of rings are configured such that the peaks of one pair are connected to the valleys of the other pair at apices of the peaks and valleys to form diamond shaped regions. In yet other patterns, there are two v-shaped elements formed by two short bar arms within the diamond-shaped elements, and a connecting bar arm connecting the two v-shaped elements.

Polymeric stent patterns

An intravascular stent assembly for implantation in a body lumen, such as a coronary artery, is designed to treat a lesion with vulnerable plaque by reducing the fibrous cap stresses. The stent includes distal, proximal, and center sections where the center section is configured to treat the vulnerable plaque. The stent consists of radially expandable cylindrical rings generally aligned on a common longitudinal stent axis and either directly connected or interconnected by one or more interconnecting links placed so that the stent is flexible in the longitudinal direction while providing high degrees of radial strength and vessel scaffolding.

Stent for treating vulnerable plaque

The invention is directed to an expandable stent for implanting in a body lumen, such as a coronary artery, peripheral artery, or other body lumen. The invention provides for an intravascular stent having a plurality of cylindrical rings connected by links with apertures and/or undulating links. The apertured links and undulating links provide the stent with a high degree of flexibility in the longitudinal direction, yet the stent has adequate vessel wall coverage and radial strength sufficient to hold open an artery or other body lumen.

An expandable stent including a light and water curable resin embedded in a stent wall wherein the wall is formed to be transmissive to light for curing the resin and transmissive to fluid for further curing of the resin. A catheter delivery system may be provided for in vivo delivery, expansion, rigidization, and installation of the stent into a body lumen.

Two stage light curable stent and delivery system

The invention is directed to an expandable stent for implanting in a body lumen, such as a coronary artery, peripheral artery, or other body lumen. The invention provides for an intravascular stent having a plurality of cylindrical rings connected by links. The rings are defined by undulations of relatively large and relatively small amplitudes wherein bar arms extend between peaks and valleys and wherein selected bar arms are non-linear. The links connecting the cylindrical rings are non-linear.

Stent with improved ring and link pattern

An expandable stent for implanting in a body lumen, such as a coronary artery, peripheral artery, or other body lumen is provided. An intravascular stent is formed by cylindrical rings connected by links. The rings have peaks and valleys from which extend straight and nonlinear bar arms, forming a figure-eight. An elemental unit is defined with straight and nonlinear bar arms, and elemental units on adjacent rings are mirror images of one another. The links have one end connected at a peak of one ring and the other end connected to a central portion of a nonlinear bar arm. Alternating rows of the links consist of nonlinear links.

Growing community of inventors

Union City, CA, United States of America

E Tina Cheng