Stryker Corporation

Tela Bio, Inc

Stout Medical Group, L.p.

Prodesco, Inc.

Stryker European Holdings I LLC

Intervalve, Inc.

Lifecell Corporation

Theken Spine, LLC

Flexmedex, LLC

USA As Represented by Secretary of the Navy

Stryker European Operations Holdings LLC

Covidien LP

Tyco Healthcare Group LP

Alphatec Spine, Incorporated

Blackstone Medical, Inc.

E Skott Greenhalgh

Michael P Wallace

John-Paul Romano

Robert J Garabedian

Robert A Kiefer

Roy Leguidleguid

Michael Paul Igoe

Travis Speicher

Robert A Van Tassel

Gregory G Brucker

Wesley Robert Pedersen

Stephen J Kleshinski

Christopher T Wagner

Wade Kevin Trexler

Robert S Schwartz

Thomas Wenchell

David M Farascioni

Aaron M Barere

Antony Koblish

Samuel Greenhalgh

Jason Park

Winnie Tang

Ronald H Garber

Matthew T Douglass

John Paul Romano

Clifford Van

Carol A Kaufmann

Brendan Farrell

Stephen H Hochschuler

John R Harper

Francesco Alfredo Larosa

Claude O Clerc

David J McQuillan

Nelson Li

Jayson Delos Santos

Jason Keiser

Greg Anderson

Boris Olevsky

James T Hogan

Michael P Igoe

John- Paul Romano

Surgical repair grafts may include at least one biotextile layer and a bioabsorbable carrier matrix including carrier particles attached to the at least one biotextile layer. The carrier particles may include an active agent. The carrier particles may include non-concentric internally aqueous chambers each surrounded by a lipid membrane. The carrier particles may be configured to release the active agent upon exposure to an aqueous fluid. The carrier particles may be attached to the at least one biotextile layer at discrete attachment sites as islands that are spaced apart from each other to provide axial compliance to the surgical repair graft during bending of the surgical repair graft.

Surgical repair graft

Vaso-occlusive apparatuses, including implants, and methods of using them to treat aneurysms. The vaso-occlusive implants described herein include one or more soft and expandable braided member coupled to a pushable member such as a coil that maybe inserted and retrieved from within an aneurism using a delivery catheter as well as a friction element between the soft braided member and the coil. The friction element allows the relatively soft and elongate implant to be pushed out of a cannula without binding up within the cannula.

Vaso-occlusive devices including a friction element

A hybrid medical device that can aid in reconstructive or augmentative surgery of the breast is disclosed. The device can utilize a suitable biological collagen tissue matrix combined with a synthetic material, for example, that can impart a high initial strength to the repair site while permitting proper healing and revitalization of the implanted device.

Surgical attachment device

Mechanical thrombectomy apparatuses, and particularly knitted rolling tube mechanical thrombectomy apparatuses configured to have improved tracking for delivery through tortious vessels are described herein. Also described herein are methods of removing clots using a mechanical thrombectomy apparatuses in which the clot is larger than the tractor portion of the mechanical thrombectomy apparatus.

Inverting thrombectomy apparatuses having enhanced tracking

Described herein are negative pressure drains configured as 'rolling' surgical drains including an invertible porous mesh having an expanded configuration so that negative pressure may be applied out of the invertible porous mesh to extend a uniform negative pressure within the body region being treated. The invertible porous mesh may then be withdrawn into the apparatus without significantly disrupting the tissue.

Rolling surgical drains

Described herein are implants (e.g., medical textiles/biotextiles) that include stitched gripping filaments to increase gripping, and methods of forming and using them. In some configurations these apparatuses may be configured as surgical grafts that may be used for soft tissue reconstruction, regeneration, or repair.

Textured medical textiles

Corner-lock stitch patterns. A mesh pattern may include a first pattern of a first upper thread and a first lower thread comprising one or more first polygonal or circular rings, and a second pattern of a second upper thread and a second lower thread comprising one or more second polygonal or circular rings. At least one of the second polygonal or circular rings may overlap with at least one of the first polygonal or circular rings at an area of overlap. The area of overlap may include a corner-lock stitch pattern in which the second upper thread and second lower thread envelop the first upper thread and the first lower thread.

Corner-lock stitch patterns

An attachment device with a radially expandable section is disclosed. The attachment device can have helical threads, for example, to facilitate screwing the attachment device into a bone. Methods of using the same are also disclosed. The attachment device can be positioned to radially expand the expandable section in cancellous bone substantially surrounded by cortical bone.

Expandable attachment device and method

Compliance control stitch patterns sewn or embroidered into biotextile or medical textile substrates impart reinforcing strength, and stretch resistance and control into such substrates. Compliance control stitch patterns may be customizable to particular patients, substrate implantation sites, particular degenerative or diseased conditions, or desired time frames. Substrates having compliance control stitch patterns sewn or embroidered into them may be used in tissue repair or tissue reconstruction applications.

Compliance control stitching in substrate materials

Materials for soft tissue repair, and in particular, material for hernia repair. These materials may be configured as an implant, such as a graft, that may be implanted into a patient in need thereof, such as a patient having a hernia or undergoing a hernia repair surgical procedure. These grafts may include a first layer comprising a substrate (e.g., mesh) and a second layer comprising a sheet of anti-adhesive material. The layers may be attached with a plurality of relatively small attachment sites that are separated by regions in which the two layers are not attached, to provide a highly compliant graft.

Hernia repair grafts having anti-adhesion barriers

Implantable tensile load-bearing grafts having synthetic components stitched through biological components are disclosed. The synthetic components can be biodegradable and/or non-biodegradable and of differing tensile strengths from each other and the biological component. Methods of making the grafts are also disclosed.

Reinforced orthopedic devices

Mechanical thrombectomy apparatuses including an inverting, rolling conveyor region ('tractor') at the distal end that are configured to grab and remove thrombus material. In particular, described herein are mechanical thrombectomy apparatuses that are adapted to prevent premature deployment of the tractor, e.g., by including a tractor hold (e.g., a housing, a lock, a clamp, etc.) or the like to secure the outer end of the tractor against and/or relative to the elongate inversion support.

Pre-loaded inverting tractor thrombectomy apparatuses and methods

The apparatuses and methods described herein relates generally to the field of active agent (drug) release from surgical grafts useful for soft tissue reconstruction, regeneration, or repair. More particularly, described herein are surgical grafts for soft tissue repair that include an active agent that is released over time while advantageously matching the biomechanical properties of tissue during healing and recovery.

Mechanical thrombectomy apparatuses (devices, systems, etc.) and methods for deploying and/or positioning them within a vessel and/or using them and/or removing a thrombus, e.g., clot, from within a vessel using them.

Inverting mechanical thrombectomy apparatuses

Inverting tube thrombectomy apparatus for removing clot that are configured to prevent compression of the apparatus that may separate the distal end of the apparatus from the clot and may make it difficult to advance the apparatus to engage with the clot, particularly in a tortious vessel. The apparatuses and methods of using them described herein may be adapted to prevent tension in the flexible tube that is rolling and inverting over the distal end of the inversion support catheter when capturing a clot. Also described herein are inverting tube thrombectomy apparatus that are configured to reload either automatically or manually within the vessel to capture additional clot material.

Inverting thrombectomy apparatuses and methods of use

Growing community of inventors

Gladwyne, PA, United States of America

E Skott Greenhalgh