Becton Dickinson and Company Limited

E Guan

Michael Vincent Quinn

Eric Schiller

Gang Ju

Anthony Economou

Johanna Torres

Anthony Enonomou

A stopper adapted for attachment with a plunger rod for use within a syringe barrel is disclosed. The stopper includes a main body defining an open rearward end and a closed front end. The open rearward end is adapted to receive a front forward end attachment portion of the plunger rod. The stopper also includes a core member integrally formed with the main body adjacent the closed front end. The core member includes a nose portion having a conical tip configured for entering an outlet opening of the syringe barrel. The closed front end of the stopper has a profile configured to cooperate with an internal surface of the syringe barrel wall to prevent reflux and reduce dead space within the barrel.

Stoppers used in pre-filled syringes

A stopper adapted for attachment with a plunger rod for use within a syringe barrel is disclosed. The stopper includes a main body defining an open rearward end and a closed front end. The open rearward end is adapted to receive a front forward end attachment portion of the plunger rod. The stopper also includes a core member integrally formed with said main body adjacent the closed front end. The core member includes a nose portion having a profile adapted to create a positive seal with an outlet opening of such syringe barrel.

Positive displacement stopper for a pre-filled syringe

A plunger rod adapted for attachment with a stopper for use with a syringe barrel is disclosed. The plunger rod includes an elongated member having a front end and a back end, the plunger rod extending along a longitudinal axis. The plunger rod includes at least one deflecting arm associated with the front end of the elongated member. The deflecting arm is capable of deflecting radially inward during insertion of the plunger rod into a stopper, and deflecting outward into contact with an inner surface of the stopper after insertion to lock the plunger rod within the stopper.

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Parsippany, NJ, United States of America

E Guan