Johns Hopkins University

Dzung H Nguyen

James Thomas Buckley

James E K Hildreth

The infectivity of a population of enveloped viruses which comprise a glycosylphosphatidylinositol-anchored protein in their membrane can be reduced by employing certain toxins such as aerolysin, alpha toxin of or enterolobin. Toxins which bind to glycosylphosphatidylinositol-anchored proteins inactivate such viruses. The toxins can be used to produce attenuated viral vaccines, to purge blood products, cells, or tissues of such viruses, and to detect viruses in samples.

Growing community of inventors

Baltimore, MD, United States of America

Dzung H Nguyen