Smithkline Beecham Corporation

Glaxo Group Limited

Galvani Bioelectronics Limited

Dwight Sherod Walker

Daniel John Chew

Allan J Clarke

Frederick Henry Fiesser

David George Doughty

Lee A Barger

David S Wagner

Michael Bernard James

Mark Austin Patrick

David Tainsh

Methods for fabricating implantable cuff electrodes for contacting or at least partially surrounding internal body tissue such as, e.g., nerves, smooth muscles, striated muscles, arteries, veins, ligamental tissues, connective tissues, cartilage tissues, bones, or other similar body tissues, structures and organs are disclosed. An example method includes preparing a substrate including an implantable cuff electrode shape, applying a mold material to the substrate, curing the mold material to form a mold, releasing the mold from the substrate, inserting at least one conductor into the mold that penetrates through the channel of the mold, pressing a formable material into the channel of the mold to form a body of an implantable cuff electrode about the at least one conductor, curing the body of the implantable cuff electrode, and releasing the body of the implantable cuff electrode from the mold.

Neural interface fabrication

An apparatus and method are provided for producing pharmaceutical and pharmaceutical-like products. The apparatus and method provide real-time monitoring of the pharmaceutical product and can provide real-time control. The apparatus and method can monitor the dosage both before and after it has been added to a carrier substrate. The apparatus and method can provide monitoring of each pharmaceutical product that is processed.

Apparatus and method for producing a pharmaceutical product

A system for use in in-situ analysis of pharmaceutical samples, said system comprising means for holding a plurality of said samples, wherein said samples are present in the form of a powder formulation; means for moving said plurality of samples along a sample path; means for generating a plurality of incident radiation pulses of different wavelength; means for illuminating at least a respective one of said samples with at least a respective one of said radiation pulses during said movement of said samples, said radiation pulse having a suitable range of radiation wavelengths capable of inducing a fluorescent response; means for detecting a first resultant fluorescence emitted from each of said samples; first control means in communication with said moving means and said incident radiation generating means for synchronizing said means for illuminating each of said samples with said moving means.

System for real-time fluorescent determination of trace elements

A remote sensor system () and method for passively sensing environmental conditions, such as temperature and humidity, uses a magnetic impulse from an AC interrogation coil () to stimulate a magnetoelastic sensor () to generate an acoustic signal (AE) at the resonant frequency of the magnetoelastic sensor (). The acoustic signal (AE) is received by amplifier (), detected and displayed (). The systems and methods are particularly suited for detecting environmental conditions in commercial pharmaceutical packaging, such as blister packs.

Magnetoacoustic sensor system and associated method for sensing environmental conditions

A system for real-time fluorescent determination of trace elements comprising transport means for moving a plurality of samples, means for generating a plurality of incident radiation pulses of different wavelength, means for illuminating at least a respective one of the samples with at least a respective one of the radiation pulses during the movement of the samples, means for detecting the resultant fluorescence emitted from each of the samples and control means for controlling the movement of the samples and the incident radiation.

Method and system for real-time fluorescent determination of trace elements

A sensor system for determining at least one environmental condition within pharmaceutical packaging comprising a base sheet with at least one pocket formed therein, a lid sheet having a pocket portion, the pocket portion being disposed proximate the pocket when the lid sheet is bonded to the base sheet; and a microelectromechanical (MEMS) sensor disposed proximate the pocket portion.

Microelectromechanical system and method for determining temperature and moisture profiles within pharmaceutical packaging

A system and method for in vitro analysis of therapeutic agents comprising a reservoir adapted to hold a therapeutic agent, a first flow cell having a first cell chamber adapted to receive at least a first sample of the therapeutic agent, a second flow cell having a second cell chamber adapted to receive at least a second sample of the therapeutic agent, the first flow cell having a first path length (b') and the second flow cell having a second path length (b&#x2033;), the first path length being substantially equal to a sensitivity factor (f)&#xd7;b&#x2033;, a membrane chamber having a biological cell membrane therein adapted to receive at least a third sample of the therapeutic agent, the membrane chamber being further adapted to detect the membrane potential of the biological cell membrane; and spectroscopic detection means for detecting the spectral characteristics of the first and second therapeutic agent samples.

System and method for in vitro analysis of therapeutic agents

An apparatus for in-situ spectroscopic analysis comprising a flow cell having a region of reasonable flow, the region of reasonable flow having a flow rate less than approximately 20% of the maximum flow rate, and first and second probes having optic cable member ends with a path length in the range of 20 &mgr;m to 1 mm that are disposed in the region of reasonable flow.

Growing community of inventors

Durham, NC, United States of America

Dwight Sherod Walker