Sadra Medical, Inc.

Boston Scientific Scimed, Inc.

Cardiothoracic Systems, Inc.

Atricure, Inc.

Maquet Cardiovascular LLC

Endoclear LLC

Nellix, Inc.

Estech, Inc. (endoscopic Technologies, Inc.)

Origin Medsystems, Inc.

Estech, Inc.

Sadra Medicl, Inc.

Eoplex Technologies, Inc.

Maguet Cardiovascular LLC

Boston Scientific Corporation

Dwight P Morejohn

Amr Salahieh

Ulrich R Haug

Hans F Valencia

Robert Adam Geshlider

Tom Saul

Brian D Brandt

Jean-Pierre Dueri

Charles S Taylor

Tamer Ibrahim

Michael J Banchieri

Daniel K Hildebrand

Jeff A Krolik

Ara Stephanian

Ivan Sepetka

Claudio Argento

Eugene Edward Reis

William Friederich Witt

Gary B Weller

Benjamin Sherman

Robert C Glines

William N Aldrich

Richard S Ginn

Federico J Benetti

Brent Ford Regan

Joshua K Wallin

David K Swanson

Albert K Chin

John J Frantzen

Kenneth J Michlitsch

Harry Leonard Green, Ii

Edward A Pineda

John D Pavlidis

Robert G Matheny

Kenneth Lance Miller

Thomas J Fogarty

John W Davis

Valavanur A Subramanian

Steven B Choi

Michael V Morejohn

John P Lunsford

Arthur A Bertolero

Michael D Hooven

Craig B Berky

Alan A Davidner

Peter K Johansson

Brad Eugene Vazales

Liming Lau

Matthew Monti

Geoffrey H Willis

Ken Watson

James M Gracy

Son M Gia

David J Paul

Robert Mason Trusty

TOm Saul

Richard M Ferrari

Brian J Bennett

Caralin R Adair

Andrea Johnson

Robert James Mosley

Christian Skieller

Harry L Green

Jon M Tanaka

Iris Leon Corbin

Brian Flores

Kushal P Vepa

Thomas L Baughman

Michael J Billig

James T McKinley

Clifton P Colwell

Christopher Zarins

Ronald Devore

Tony Wong

Ivan Septeka

Susan W Vican

Mike J Banchieri

James A Magovern

Lawrence W Hu

Paul Cherkas

Bhupendra Shah

Stefan Stefanov

Edmund J Morrissey, Iii

Robert A Gleshlider

Sue W Vican

Eric Reeser

Harry Leonard Ii Green

Anthony Sticca

Kimberly Cunningham

Dwayne Griffin

Richard Tefo

Edwarda Pineda

William F Witt

Brent Regan

Robert A Geshlider

Jeff Krolik

A surgical system for ablating a tissue, the system comprising: (a) an ablation mechanism comprising a first electrode and an opposed second electrode, wherein the ablation mechanism is configured to receive a tissue between the first electrode and the second electrode, and wherein at least one of the first electrode and the second electrode is movable to allow the first electrode and the second electrode to accommodate variable tissue thicknesses therebetween; and (b) a clamping mechanism configured to release and apply clamping pressure to the tissue between the first electrode and the second electrode, where the ablation mechanism is configured to automatically individually adjust at least one of an ablation energy output of the first electrode and an ablation energy output of the second electrode to accommodate variable tissue thicknesses between the first electrode and the second electrode.

Stabilized ablation systems and methods

Tissue treatment systems include an actuator handle assembly coupled with a clamp assembly having a first jaw mechanism and a second jaw mechanism. A first jaw mechanism includes a first flexible boot, a first flexible ablation member coupled with the first flexible boot, and a first rotatable jawbone disposed within the first flexible boot. A second jaw mechanism comprises a second flexible boot, a second flexible ablation member coupled with the second flexible boot, and a second rotatable jawbone disposed within the second flexible boot.

Adjustable clamp systems and methods

Surgical systems and methods for administering an ablation treatment and other therapeutic or diagnostic protocols to a patient tissue involve a flexible stabilizer mechanism having an inner recess and an ablation mechanism coupled with the stabilizer mechanism.

Embodiments of the present invention encompass systems and methods for delivering ligatures to anatomical features of a patient. Exemplary ligature delivery systems for use in delivering a ligature to a left atrial appendage ligature include an elongate support mechanism having a proximal portion and a distal portion, a flexible hoop assembly, and a cinchable constriction member. The flexible hoop assembly can be coupled with the distal portion of the elongate support mechanism, and can include a support body coupled with a support frame. The support frame can be biased to hold the support body in a trailing configuration, whereby a free portion of the support body is disposed proximal to the distal portion of the elongate support mechanism. The support frame of the flexible hoop assembly can be coupled with the distal portion of the elongate support mechanism. The support body can be configured to support the cinchable constriction member and a loop of the left atrial appendage ligature.

Systems and methods for left atrial appendage closure

An example system for applying an occlusion clip to an anatomical structure may include a visualization tool configured to allow visualization of an anatomical structure using a scope; a clip applier configured to apply an occlusion clip on the anatomical structure; an introducer connectable to the clip applier and configured to aid in positioning the clip applier; and a positioner configured to apply at least one of a linear force and a torsional force to at least one of the clip applier and the clip.

Clip application system and method

An end effector positioning mechanism for a surgical device may include an articulation mechanism including a plurality of tiltable segments disposed generally in a longitudinal row between an elongated shaft of a surgical device and an end effector of the surgical device. Each of the plurality of segments may be generally in the form of a flattened disk. At least one of the segments may include a proximal surface and/or a distal surface that is substantially planar and is oriented substantially orthogonally with respect to a central axis of the articulation mechanism. At least one of the segments may include a proximal surface and/or a distal surface including two transversely oriented, generally planar surfaces that meet along a substantially diametric peak.

End effector positioning mechanism

Exemplary scope systems and methods involve a cannula assembly, a sheath assembly, and a tubing set. A cannula assembly, which may be a non-magnetic scope cap assembly, can include a cannula body, a proximal housing having a strap, an optical window, and a luer for suction or flushing. A cannula body may include a first lumen or scope channel for receiving a visualization device such as an endoscope or laparoscope, a distal end having suction or flushing flush apertures, and a second lumen for providing fluid communication between the apertures and the luer. Exemplary magnetic introducer systems and methods involve a cannula assembly, a sheath assembly, a tubing set. In some cases, the cannula assembly of a magnetic introducer system can be a magnetic scope cap assembly. In addition to cannula and sheath assemblies, magnetic introducer systems can include a magnetic introducer tubing assembly and a stylet assembly.

Scope and magnetic introducer systems and methods

Medical devices and instruments, particularly pericardial access systems and devices and related methods are disclosed. Some example pericardial access devices may include a distally located, expandable skirt configured to engage the pericardium. When extended, the skirt may be wider than the tubular body of the device. Some example pericardial access devices may include an at least partially transparent, repositionable tip.

Pericardial access

Embodiments of the present invention encompass systems and methods to prevent complications from atrial fibrillation by preventing or reducing the likelihood of blood flow out of the left atrial appendage, to eliminate a possible source of aberrant electrical circuits, or both. Accordingly, techniques are provided for delivering ligature loops or closure means to the left atrial appendage, and to other anatomical structures of a patient which may be desirable in other surgical procedures.

Left atrial appendage treatment systems and methods

Apparatus for endovascularly replacing a patient's heart valve, including: a replacement valve adapted to be delivered endovascularly to a vicinity of the heart valve; an expandable anchor adapted to be delivered endovascularly to the vicinity of the heart valve; and a lock mechanism configured to maintain a minimum amount of anchor expansion. The invention also includes a method for endovascularly replacing a patient's heart valve. In some embodiments the method includes the steps of: endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve; expanding the anchor to a deployed configuration; and locking the anchor in the deployed configuration.

Replacement valve and anchor

In at least one embodiment, a medical device can comprise an elongate outer sheath that extends along a sheath longitudinal axis and defines a central lumen extending therethrough, the elongate outer sheath can comprise a proximal sheath portion and a distal sheath portion. A first guidewire can comprise a first guidewire end and a second guidewire end, the first guidewire can extend from the first and second guidewire ends through the central lumen and can form a distal looped portion. An occlusion device can be disposed at a distal end of an elongate flexible shaft. The elongate flexible shaft can extend from the proximal sheath portion through the central lumen. The occlusion device can include a guide lumen through which the first guide wire passes.

Medical devices

The present invention provides apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an expandable anchor configured for endovascular delivery to a vicinity of the patient's heart valve. In some embodiments, the replacement valve is adapted to wrap about the anchor, for example, by everting during endovascular deployment. In some embodiments, the replacement valve is not connected to expandable portions of the anchor. In some embodiments, the anchor is configured for active foreshortening during endovascular deployment. In some embodiments, the anchor includes expandable lip and skirt regions for engaging the patient's heart valve during deployment. In some embodiments, the anchor comprises a braid fabricated from a single strand of wire. In some embodiments, the apparatus includes a lock configured to maintain anchor expansion.

Everting heart valve

The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; and applying an external non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to change the shape of the anchor, such as by applying proximally and/or distally directed force on the anchor using a releasable deployment tool to expand and contract the anchor or parts of the anchor. Another aspect of the invention provides an apparatus including a replacement valve; an anchor; and a deployment tool comprising a plurality of anchor actuation elements adapted to apply a non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to reshape the anchor.

Methods and apparatus for endovascularly replacing a heart valve

Growing community of inventors

Davis, CA, United States of America

Dwight P Morejohn