Orchid Chemicals & Pharmaceuticals Limited

Orchid Research Laboratories Limited

Durairaj Peter Bhakiaraj

Sriram K Rajagopal

Ravikumar Tadiparthi

Venkatesan Parameswaran

Virendra Kachhadia

Sukunath Narayanan

Ganapavarapu Veera Raghava Sharma

Uma Ramachandran

Sathya Narayana Thara

Venkatesan Janarthanam

Maruthikumar Narayanam

Sathyanarayana Gadde

Gaddam Om Reddy

Gopalan Balasubramanian

Shridhar Narayanan

Sanjeev Saxena

Sappanimuthu Thirunavukkarasu

Akella Satya Surya Visweswara Srinivas

Kilambi Narsimhan

Om Reddy Gaddam

Lolaknath Santosh Vishwakarma

Narayanan Surendran

Kilambi Narasimhan

Thirunavukkarasu Sappanimuthu

Visweswara Akella Satya Surya Srinivas

Ganapavarapu Veera Sharma

Visweswara Akella Srinivas

Described are novel heterocyclic compounds of the general formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts, pharmaceutical compositions, metabolites and prodrugs thereof. These compounds are useful in the treatment of immunological diseases, inflammation, pain disorder, rheumatoid arthritis; osteoporosis; multiple myeloma; uveititis; acute and chronic myelogenous leukemia; atherosclerosis; cancer; cachexia; ischemic-induced cell damage; pancreatic beta cell destruction; osteoarthritis; rheumatoid spondylitis; gouty arthritis; inflammatory bowel disease; ARDS; psoriasis; Crohn's disease; allergic rhinitis; ulcerative colitis; anaphylaxis; contact dermatitis; muscle degeneration; asthma; COPD; bone resorption diseases; multiple sclerosis; sepsis; septic shock; toxic shock syndrome and fever. More particularly these compounds are useful as PDE4 inhibitors and are useful for treating PDE4 mediated diseases. 

Pyrimidine compounds and their uses

Novel heterocyclic compounds of the general formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts, pharmaceutical compositions, metabolites and prodrugs thereof are described. These compounds are useful in the treatment of immunological diseases, inflammation, pain disorder, rheumatoid arthritis; osteoporosis; multiple myeloma; uveititis; acute and chronic myelogenous leukemia; atherosclerosis; cancer; cachexia; ischemic-induced cell-damage; pancreatic beta cell destruction; osteoarthritis; rheumatoid spondylitis; gouty arthritis; inflammatory bowel disease; adult respiratory distress syndrome (ARDS); psoriasis; Crohn's disease; allergic rhinitis; ulcerative colitis; anaphylaxis; contact dermatitis; muscle degeneration; asthma; COPD; bone resorption diseases; multiple sclerosis; sepsis; septic shock; toxic shock syndrome and fever. More particularly these compounds are useful as PDE4 inhibitors, and useful for treating PDE4 mediated diseases. 

Heterocycles

Growing community of inventors

Chennai, India

Durairaj Peter Bhakiaraj