Kansas State University Research Foundation

Reid Industries

Duane Davis

Deryl L Troyer

Mark L Weiss

Kathy E Mitchell

Stefan H Bossmann

David Buzby

John McKenney

Daryl L Troyer

Jianhong Huang

Kevin Booze

Andrew Elliott

Immunocompetent animal models having immunological tolerance to a xenograft and methods of producing the same. The animal models are tolerized to the xenograft in the pre-immune, fetal or embryonic stage, followed by transplanting the xenograft into the animal in the post-natal stage, such that the post-natal animal is immunologically tolerant to the xenograft, while remaining immunocompetent.

Immune competent models of human disease

Stem cells from human sources can have a variety of useful applications in disease treatment and biotechnology. More particularly the umbilical cord matrix cell cultures of the invention have a variety of totipotent, pluripotent, or multipotent cells for a variety of end uses from a non-controversial, universally available, species-specific source. The technology can have application to any amniotic animal, including agricultural and laboratory animals and humans. The invention relates to isolating the stem cells, culturing the stem cells, maintaining the stem cells, transforming the stem cells into useful cell types using genetic or other transformation technologies, stem cell and tissue banking and using untransformed or transformed cells in disease treatment.

Cultures, products and methods using umbilical cord matrix cells

Growing community of inventors

Westmoreland, KS, United States of America

Duane Davis