Ethicon, Gmbh

Saint-gobain Performance Plastics Corporation

Cilag International Gmbh

Mentor Worldwide LLC

Saint-gobain Performance Plastics Corporatoin

Duan Li Ou

Leo B Kriksunov

Frank Richard Cichocki, Jr

Christophe Vailhe

Robert J Tannhauser

Clifford Dwyer

Alexander M Cannara

Frank Cichocki

Lamar Kirchhevel

Joseph Henry Contiliano

Charles D Klann

Inas Alhamyery

Thien Nguyen

Robert Anthony Rousseau

Julian A Quintero

Mark W Simon

Krasimira Hristov

Glenn R Cook

Scott Richard Johnson

Thomas Nering

Leland E Moll

Bryan D Rud

Brian Blasic

Carolyn J Mordas

Krasmira Hristov

Jr Frank R Cichocki

Frank R Cichocki

Novel compositions and systems for closure of wounds with antimicrobial effectiveness provide devices of improved flexibility and elasticity and are readily applied to wound sites or over wound closure devices. A novel platinum catalyst comprising platinum tetramethyldivinyl disiloxane diethyl maleate complex for use in such compositions provides for rapid curing on topical surfaces such as skin and bonds to such surfaces in about 2-5 minutes.

Antimicrobial topical skin closure compositions and systems

Novel, lubricious coatings for medical devices are disclosed. The coatings provide improved lubricity and durability and are readily applied in coating processes a low temperatures that do not deform the device. The present invention is also directed to a novel platinum catalyst for use in such coatings. The catalyst provides for rapid curing, while inhibiting cross-linking at ambient temperatures, thereby improving the production pot life of the coatings.

Low temperature cured silicone lubricious coatings

A method of making an implantable prosthesis includes applying a gelling enhancer layer over an inner surface of a wall of a silicone shell having anterior and posterior walls surrounding an interior volume. The method includes filling the interior volume of the shell with a silicone gel and curing the silicone gel. The cured silicone gel that is located within a zone that is in the vicinity of the gelling enhancer layer has a higher level of cohesiveness than the cured silicone gel that is located outside the zone. The zone of the silicone gel having the higher level of cohesiveness has a thickness of 2-10 mm. The silicone gel located outside the zone has a first concentration level of a gelling enhancer and the silicone gel located within the zone has a second concentration level of the gelling enhancer that is 5%-300% greater than the first concentration level.

Methods of making implants having gel zones with higher levels of cohesiveness for eschewing scalloping, dimpling, and wrinkling

A novel two-step process for batch coating surgical needles with cross-linked silicone coatings is disclosed. The surgical needles are cured using a two-step process. The coatings on the needles are partially cured in the first step and mechanically separated. The coatings on the needles are then fully cured in the second step.

Two-step batch process for coating surgical needles

Novel, lubricious coatings for medical devices are disclosed. The coatings provide improved lubricity and durability, and are readily applied in coating processes. The present invention is also directed to a novel platinum catalyst for use in such coatings. The catalyst provides for rapid curing, while inhibiting cross-linking at ambient temperatures, thereby improving the production pot life of the coatings.

Rapid cure silicone lubricious coatings

Systems and methods for coating surgical needles are provided.

Surgical coated needles

A blackened surgical needle made by the method of treating blackened surgical needles, comprising the steps of: a. determining that a blackening process may have produced loose black oxide particles on the blackened surgical needle; b. placing at least one blackened surgical needle having loose black oxide particles on its surface into a bath, wherein the bath comprises: i. an effective amount of citric acid to remove loose black oxide particles from the at least one blackened surgical needle; and ii. a source of ultrasound; and c. applying the ultrasound in the bath for a time sufficient to remove loose black oxide particles from the surface of the at least one needle and wherein the contents of the bath are maintained at a pH below 3.25.

Non-hazardous cleaning solution and process for cleaning blackened needles

The present disclosure provides a coating apparatus and method for applying a coating of a therapeutic agent, comprising an openable and sealable device compartment, a therapeutic agent positioned in communication with the device compartment, a thermal source for vaporizing the therapeutic agent, and a vacuum source in fluid communication with the device compartment.

Operating room coating applicator and method

Novel compositions and systems for closure of wounds are disclosed. The compositions provide devices of improved flexibility and elasticity and are readily applied to wound sites or over wound closure devices. The present invention is also directed to a novel platinum catalyst for use in such compositions. The catalyst provides for rapid curing on topical surfaces such as skin and bonds to such surfaces in about 2-5 minutes.

Topical skin closure compositions and systems

A system for dispensing a curable composition includes a dual barrel syringe including a first syringe barrel with a first plunger, and a second syringe barrel with a second plunger. A static mixer is connected with distal ends of the first and second syringe barrels. The first and second plungers are moveable toward the distal ends of the first and second syringe barrels for expelling first and second components of a curable composition from the distal ends of the barrels into the static mixer for mixing the components to form the curable composition. A flexible spreader connected with a distal end of the static mixer has a flat dispensing opening, and a plurality of channels extending to the flat dispensing opening to dispense the curable composition. A hot gas blower generates a hot gas stream flowing distally over the distal end of the flexible spreader for curing the curable composition.

Systems, devices and methods for dispensing and curing silicone based topical skin adhesives

The present disclosure provides a coating applicator operable to apply a coating of a therapeutic agent upon an object comprising an openable and sealable device compartment, a therapeutic agent positioned in communication with the device compartment, an atomizer operable to atomize the therapeutic agent, and a source of vacuum in communication with the device compartment. The coating applicator may further comprise a drier, and the drier may comprise an arrangement to operate the source of vacuum for a time sufficient to promote drying of applied therapeutic agent. Deposition of the atomized therapeutic agent may be promoted by contacting the atomized therapeutic agent while the object is in a chilled condition and by contacting the object with atomized therapeutic agent while the atomized therapeutic agent is in a heated condition. Related methods are also disclosed.

A method of reducing surgical site infection (SSI), using a coated medical device having a tissue penetrating surface and an abradable coating on the medical device comprising at least one antimicrobial agent in the coating.

Abradable therapeutic coatings and devices including such coatings

Provided are rapidly cross-linkable silicone compositions, systems, kits, and methods for filling implanted medical devices in situ, the implanted medical devices, including for example, body implants and tissue expanders, the compositions including a platinum divinyl disiloxane complex; a low viscosity vinyl terminated polydimethylsiloxane; a low viscosity hydride terminated polydimethylsiloxane; and a silicone cross-linker, where the rapidly cross-linkable silicone composition has a viscosity of &#x2264;150 cPs for &#x2265;1 min. post-preparation and &#x2264;300 cPs&#x2264;5 min. post-preparation, at ambient temperature.

Silicone compositions rapidly cross-linkable at ambient temperatures and methods of making and using same

Provided are rapidly cross-linkable silicone foam compositions, kits, and methods for filling implanted medical devices in situ or in vivo, the implanted medical devices, including for example, body implants and tissue expanders, the compositions including a platinum divinyl disiloxane complex; a low viscosity vinyl terminated polydimethylsiloxane; a low viscosity hydride terminated polydimethylsiloxane; a silicone cross-linker; and a gas and/or gas-filled microcapsules, where the rapidly cross-linkable silicone foam composition has a viscosity of &#x2264;150 cPs for &#x2265;1 min. post-preparation and &#x2264;300 cPs&#x2264;5 min. post-preparation, at ambient temperature.

Growing community of inventors

Warren, NJ, United States of America

Duan Li Ou