University of Florida Research Foundation, Incorporated

Du Chen

Jose Carlos Principe

John Gregory Harris

Dazhi Wei

A method for coding time signals based on generating an asynchronous biphasic pulse train is provided. The method includes generating response signals based upon one or more input signals. A pulse comprises a positive pulse if a voltage of the response signal is greater than a predetermined positive voltage threshold. A pulse comprises a negative pulse if the voltage of the response signal is less than a predetermined negative voltage threshold. The method further includes a method for the reconstruction of a uniformly sampled version of the original signal.

Device and methods for biphasic pulse signal coding

An amplifier-based system having pulsed output includes an amplifier for amplifying a time varying voltage signal to produce an output voltage signal. A voltage-to-current (V-I) converter converts the output voltage signal into a current signal. An output stage including a current integrator integrates the current signal to generate an integrated voltage. An amplitude to time converter generates a pulse train from the integrated voltage, wherein a timing of the pulses in the pulse train represents the original time varying voltage signal. The pulse train representation permits transmission and accurate remote reconstruction of the original time varying voltage signal, such as signals generated by electrodes implanted inside a subject, including neural signals.

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Du Chen