Massachusetts Institute of Technology

Smiths Detection Inc.

Smiths Detection-edgewood, Inc.

Drew Chapman Brown

Eric Scott Clasen

Mark Alexander Hollis

James Douglas Harper

Michael Joseph Rello

John C Schmidt

Laura T Bortolin

Johanna Bobrow

Richard Karl Pallo

Lalitha Parameswaran

Carrie Lynn Holmes

Tiffany Howland

Lisa Miller

An apparatus for preparing a nucleic acid component of a sample for amplification includes a porous support having an agent that deactivates a nucleic acid amplification inhibitor component of the sample. The apparatus further includes a housing with an opening and defining an interior. The interior of the housing is in fluid communication with the porous support, and at least a portion of a fluid directed through the opening is directed through at least a portion of the porous support. The apparatus also includes a magnetic substrate for separating nucleic acid from a sample.

Apparatus for isolating a nucleic acid from a sample

A simplified Polymerase Chain Reaction (PCR) sample preparation apparatus and method of using a PCR sample preparation for both liquid and dry samples. A portable apparatus comprising a handle removably attached to a wand assembly. The handle includes a cover and a swab with an absorbent material. The wand assembly includes a buffer container for a buffer that is ruptured by a spike when the holder is inserted into the wand assembly. The apparatus may include a waste container removably attached to a tube comprising a plunger, a safety clip to prevent the plunger from depressing, and a port for introduction of a liquid sample. A filter on the waste container collects a specimen of the liquid sample for preparation as described above.

PCR sample preparation holder and method

Growing community of inventors

Towson, MD, United States of America

Drew Chapman Brown