Massachusetts Institute of Technology

Novo Nordisk A/s

The Brigham and Women's Hospital, Inc.

Technische Universitāt Wien

Drago Sticker

Robert Samuel Langer

Carlo Giovanni Traverso

Niclas Roxhed

Brian Mouridsen

Jacob Wainer

Jorrit Jeroen Water

Peter Ertl

Yi Lu

Bozhidar Nikolaev Kozhuharov

Kim Frandsen

Adam Bohr

Torben Sebastian Last

Graham Arrick

Jacob Pyung Hwa Jepsen

Sarah Lechner

Siheng You

Cody Cleveland

Declan Gwynne

Aghiad Ghazal

A drug delivery device for administration to a subject is provided. In some embodiments, the drug delivery device includes a reservoir containing an active pharmaceutical ingredient and a potential energy source. The drug delivery device also includes a trigger operatively associated with the potential energy source, where the trigger is configured to actuate at a predetermined location within the subject. The drug delivery device also includes a rupturable membrane disposed along a flow path extending between the reservoir and an outlet, where the membrane is configured to rupture when the trigger is actuated. Once the trigger is actuated, the potential energy from the potential energy source may be released to expel the active pharmaceutical ingredient in a jet through the outlet.

Drug delivery device

The present invention relates to a microfluidic device for creating within a cell assembly a cell-free area, comprising at least one cell chamber, wherein the at least one cell chamber comprises: &#x2014;a fluid inlet for introducing fluid into the cell chamber, &#x2014;a first area, &#x2014;a second area, &#x2014;at least one mechanical excluding means for excluding cells from the first area of the chamber and being operable between an excluding position and a releasing position optionally via an actuation line, wherein the second area of the cell chamber is outside of the operation range of the mechanical excluding means.

Microfluidic device

Growing community of inventors

Malmö, Sweden

Drago Sticker