Merck + Co., Inc.

Hyclone Labortories, Inc.

Doyle W Stewart

Brett L Allred

Mark S Rienstra

Anand Ekambaram

Wendy L Radcliff

The present invention relates to a package for storing, mixing, resuspending and dispensing sterile or non-sterile solutions or suspensions and comprises a sterilizable bag having fittings which provide for the introduction and exit of fluids and solids, as well as means for resuspending and stirring the fluids. Additionally, structural support means are provided for shipment, filling and dispensing. Unlike conventional stainless steel equipment, the system is disposable, does not require cleaning, provides for safe, rapid and accurate resuspension of suspended solids and can accommodate a wide range of liquid volumes.

Disposable storage, transport and resuspension system

A resuspension system includes a flexible media bag removably disposed within a rigid support container. The media bag includes an inlet port, an outlet port, and an assembly for mixing and resuspending fluids within the media bag. The assembly for mixing and resuspending includes a peristaltic pump which withdraws fluid from the media bag and introduces the fluid back into the media bag through a mixing block. The mixing block includes a housing having a conical top surface that extends from a hose barb to a circular sidewall. An inlet passageway vertically extends through the hose barb into the housing. A plurality of curved outlet channels extend from the inlet passageway through the circular sidewall of the housing. The outlet channels exit at such an orientation that as fluid passes through the outlet channels, a vortex flow pattern is created within the media bag.

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Hyrum, UT, United States of America

Doyle W Stewart