Institute of Nuclear Energy Research, Atomic Energy Council, Executive Yuan, R.o.c

Atomic Energy Council

Dow-Che Chen

Wuu-Jyh Lin

Jenn-Tzong Chen

Ting-Shien Duh

Mao-Hsung Chang

Kuo-Yuan Chu

Chyng-Yann Shiue

Shiou-Shiow Farn

Li-Yuan Huang

Yean-Hung Tu

Ping-Yen Huang

A radiocontrast agent for tau protein is provided. The agent is selectively and strongly bound to tau protein and its tangle found in brain diseases like Alzheimer's disease (AD). The agent is especially suitable to be used in PET imaging for brain diseases. Or, the agent can be used to inhibit tau protein overexpressive and, thus, stop the proceeding of brain disease.

Compound of radiocontrast agent for tau protein

A liquid and a gas is constantly filled into a target chamber of a target. Then the liquid and the gas flow around the chamber and are flown out. By doing so, the target is effectively cooled down.

Circulated cooled target

Growing community of inventors

Taoyuan County, Taiwan

Dow-Che Chen