University of Florida Research Foundation Inc

The United States of America As Represented by the Secretary of

Other

The United States of America As Represented by the Department of

The United States of America As Represented by the United States

Dov Borovsky

David A Carlson

Arnold De Loof

Peter Verhaert

Dany Bylemans

John Grant Bennett

Alan E Brandt

Russell J Linderman

Sabine Maria Isidore Nauwelaers

Yaaquov Schlesinger

The present invention discloses novel pest control compounds comprising NPF polypeptides and methods for using such compounds in the control of pests.

Neuropeptides and their use for pest control

The subject invention provides materials and methods for controlling pests. In a preferred embodiment the pests are agricultural pests and, in particular, insect pests. Specifically exemplified herein are materials and methods for the control of insect larvae.

Materials and methods useful for the control of insect larvae

Novel pest control compounds, compositions comprising such compounds, and methods for using such compounds and compositions against a variety of pests, including pests of agricultural crops.

Compositions and methods for controlling pests

The subject invention provides materials and methods for the control of pests. Specifically exemplified is the use of recombinant hosts to control mosquito larvae. These hosts, which may be, for example yeast or algae, can be transformed so that they express a pesticidal polypeptide which controls mosquito larvae. These transformed microbes can then be applied to surface waters where mosquito larvae are likely to be found.

Transformed cells useful for the control of pests

The subject invention pertains to novel pest control compounds. Specifically exemplified herein are peptides having 2 to 5 amino acids. The subject peptides are useful against a variety of pests, including pests of agricultural crops.

Pesticidal peptides

The subject invention concerns novel peptides which have the property of interfering with the biosynthesis of the enzyme trypsin. This property enables the use of these peptides to, for example, inhibit the formation of progeny in blood-ingesting insects, since trypsin is an essential enzyme for food digestion which provides the essential building blocks for egg development in such insects.

Materials and method for control of pests

DNA encoding peptide hormone that inhibits digestion in insects

The subject invention concerns novel peptides which have the property of interfering with the biosynthesis of the enzyme trypsin and the biosynthesis of the hormone ecdysone. This property enables the use of these peptides to, for example, inhibit the formation of progeny in blood-ingesting insects, e.g., Neobellieria, since trypsin is an essential enzyme for food digestion which provides the essential building blocks for egg development in such insects.

Methods and compositions for the control of the flesh fly

Materials and methods for control of pests

The subject invention concerns three novel peptides which have the property of interfering with the biosynthesis of the enzyme trypsin in an insect gut. This property enables the use of these peptides to inhibit the formation of progeny in blood-ingesting insects, since trypsin is an essential enzyme for food digestion which provides the essential building blocks for egg development in such insects.

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Vero Beach, FL, United States of America

Dov Borovsky