Other

The Gillette Company

The Procter Gamble Company

Douglas Shander

Gurpreet S Ahluwalia

James P Henry

Peter Styczynski

Margaret G Funkhouser

F Eugene Harrington

Roman V Rariy

Anwar Jardien

Hermes Van Der Lee

Miklos M Breuer

Cheng Shine Hwang

Vera R Usdin

Edwin G Kaszynski

Diana Marks-Del Grosso

Mary C Whitmore

Natalia Botchkareva

Diana M-d Grosso

Edward Kaszynski

A method of reducing hair growth includes topical application of a TRPM8 and/or a TRPA1 agonist, alone or in conjunction with heat.

Reduction of hair growth

Compositions including a conjugate of &#x3b1;-difluoromethylornithine can be applied topically to reduce hair growth.

A topical composition useful for reducing in hair growth includes &#x3b1;-difluoromethylornithine and a dermatologically acceptable vehicle comprising at least 4% by weight of a polyoxyethylene ether having the chemical formula R(OCHCH)OH, where R is a saturated or unsaturated alkyl group including from 6 to 22 carbon atoms and b is from 2 to 200.

Mammalian hair growth can be reduced by topical application of an inhibitor of fatty acid metabolism.

A method of reducing the rate of mammalian hair growth includes topically applying a composition containing a sulfhydryl reactive compound to the skin.

Method of reducing hair growth employing sulfhydryl active compounds

Hair growth can be reduced using a composition including optically pure L-&agr;-difluoromethylornithine or &agr;-difluoromethylornithine including a preponderance of L-&agr;-difluoromethylornithine.

Mammalian hair growth is reduced by applying to the skin a composition including an inhibitor of an enzyme involved in arachidonic acid metabolism.

Inhibition of hair growth

Mammalian hair growth is reduced by applying to the skin a composition including an inhibitor of cyclooxygenase.

Mammalian hair growth is reduced by applying to the skin a composition including an inhibitor of 5-lipoxygenase.

A method of reducing hair growth in a mammal includes applying, to an area of skin from which reduced hair growth is desired, a dermatologically acceptable composition containing a suppressor of the metabolic pathway for the conversion of glucose to acetyl-CoA.

A method of inhibiting hair growth in a mammal includes applying, to an area of skin from which reduced hair growth is desired, a dermatologically acceptable composition containing a non-steroidal suppressor of angiogenesis.

Mammalian hair growth is reduced by applying to the skin an inhibitor of hypusine biosynthetic pathway.

Mammalian hair growth is reduced by inhibiting the activity of a matrix metalloproteinase in the skin.

Reduction of hair growth using inhibitors of matrix metalloproteinases

A method of reducing hair growth in a mammal includes applying, to an area of skin from which reduced hair growth is desired, a dermatologically acceptable composition containing a compound that inhibits the formation of glycoproteins, proteglycans, or glycosaminoglycans in an amount effective to cause a reduction in hair growth.

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Gaithersburg, MD, United States of America

Douglas Shander