E.i. Dupont De Nemours and Company

Butamax Advanced Biofuels LLC

Dupont Displays Inc

Douglas Robert Anton

William Frank Graham

Michael J Darmon

Richard R Thomas

Gary Delmar Jaycox

Bruce Aaron Diner

Jeffery W Johnson

Michael Joseph Michalczyk

Sape Kwesi Quashie

Robert DiCosimo

Michael Charles Grady

Francis J Woerner

Jelena Cirakovic

Hong Peng Wang

William Brown Farnham

Ming-Hong Hung

Frank J Weigert

Ronald James McKinney

Stephen R Fahnestock

Alberto Goenaga

Brian Michael Roesch

Jack R Kirchner

Charles D Lang

Keith H Burlew

Kari A Fosser

Paul Anthony Sant

Charles Kenneth Taylor

Stephane Francois Bazzana

Stephen Sorich

Allen Capron Sievert

Carl G Krespan

Paul R Resnick

Pierre E Rouviere

William Howard Tuminello

Joe Douglas Druliner

Tanja Maria Gruber

Scott D Cunningham

Michael Dauner

Yongqing Huang

Steven D Doig

John W Hallam

William Wesley Bennett, Jr

Richard Ronald Thomas

Sape Kewsi Quashie

Michael Joseph Michalczk

The invention relates to a method for producing butanol through microbial fermentation, in which the butanol product is removed by extraction into a water immiscible organic extractant composition during the fermentation. The invention also relates to a method for producing butanol through microbial fermentation, in which the butanol product is removed during the fermentation by extraction into a water-immiscible extractant composition comprising a first solvent having a butanol partition coefficient of at least 3, and a second solvent having a butanol partition coefficient, wherein the butanol partition coefficient of the first solvent is higher than the butanol partition coefficient of the second solvent. Optionally, the first solvent has a higher concentration of hydrogen bonding sites than the second solvent. The invention further relates to a composition including butanol in the water immiscible organic extractant composition described above.

Method for producing butanol using extractive fermentation

Provided herein are processes comprising providing a fermentation medium comprising a fermentable carbon source, a recombinant microorganism comprising an engineered butanol biosynthetic pathway, and butanol; contacting said fermentation medium with an extractant composition comprising an effective amount of antioxidant or antioxidant-like compound, whereby at least a portion of the butanol in the fermentation medium partitions into the extractant; recovering at least a portion of the butanol and extractant composition from the fermentation medium; recycling the extractant composition recovered in (c) one or more times in the fermentation medium; optionally adjusting the effective amount of antioxidant or antioxidant-like compound in the extractant composition, whereby the rate of oxidation or effect of oxidized products in the recycled extractant composition is substantially reduced and/or avoided such that the extractant composition may be recycled.

Recyclable extractant compositions

In an alcohol fermentation process, oil derived from biomass is chemically converted into an extractant available for in situ removal of a product alcohol such as butanol from a fermentation broth. The glycerides in the oil can be chemically converted into a reaction product, such as fatty acids, fatty alcohols, fatty amides, fatty acid methyl esters, fatty acid glycol esters, and hydroxylated triglycerides, and mixtures thereof, which forms a fermentation product extractant having a partition coefficient for a product alcohol greater than a partition coefficient of the oil of the biomass for the product alcohol. Oil derived from a feedstock of an alcohol fermentation process can be chemically converting into the fermentation product extractant. The oil can be separated from the feedstock prior to the feedstock being fed to a fermentation vessel, and the separated oil can be chemically converted to a fermentation product extractant, which can then contacted with a fermentation product comprising a product alcohol, whereby the product alcohol is separated from the fermentation product.

Extraction solvents derived from oil for alcohol removal in extractive fermentation

An alcohol fermentation process and composition that includes production of alcohol esters by esterification of product alcohol in a fermentation medium with a carboxylic acid (e.g., fatty acid) and a catalyst (e.g., lipase) capable of esterifying the product alcohol, such as butanol, with the carboxylic acid to form the alcohol esters. The alcohol esters can be extracted from the fermentation medium, and the product alcohol recovered from the alcohol esters. The carboxylic acid can also serve as an extractant for removal of the alcohol esters from the fermentation medium.

Production of alcohol esters and in situ product removal during alcohol fermentation

Diols produced in fermentation are processed in broth by esterification of the product diol with a carboxylic acid (e.g., fatty acid) and a catalyst (e.g., lipase) capable of esterifying the product diol, such as 1,3-propanediol, with the carboxylic acid to form the diol esters. The diol esters can be extracted from the broth, and the product diol recovered from the diol esters. The carboxylic acid can also serve as an extractant for removal of the diol esters from the fermentation medium.

Enzymatic production of alcohol esters for recovery of diols produced by fermentation

Peptide-based reagents comprising at least one tooth surface-binding peptide for delivery of at least one polymer-coated white colorant to the surface of teeth are provided. The peptide-based reagent may comprise at least one tooth-binding peptide coupled to, either directly or through one or more spacers, a polymer-binding peptide capable of binding to the polymeric coating on a polymer-coated white colorant. Methods of delivering a polymer-coated white colorant to a tooth surface are also provided as well as oral care compositions comprising the present peptide-based reagents. The peptide-based reagents may be used in conjunction with at least one polymer-coated white colorant to improve the cosmetic appearance of teeth.

Peptide-based tooth whitening reagents

Provided herein are uncured dental composites suitable for, among other things, filling cavities in teeth.

Materials leading to improved dental composites and dental composites made therefrom

There is provided a process for forming a contained second layer over a first layer, including the steps:

Process for making contained layers and devices made with same

Oral care compositions, oral care systems, oral surface-binding peptides, and a method for applying particles to an oral surface are provided. The oral care system comprises at least one peptidic component comprising a first binding element having affinity for an oral surface and a second binding element having affinity for a ligand property of a particle.

Peptide compositions for oral care systems

This invention relates to composite materials for restorative dentistry. More particularly, it relates to new components for dental composites, which impart an attractive combination of good mechanical properties and low shrinkage.

A method for repairing a basecoat/clearcoat finish or coating comprised of a fluorinated organosilane topcoat. A fluorinated urethane additive is added to the fluorinated organosilane topcoat composition to improve recoat adhesion with the repair basecoat.

Method for achieving recoat adhesion over a fluorinated topcoat

Growing community of inventors

Wilmington, DE, United States of America

Douglas Robert Anton