Malvern Panalytical Inc.

Douglas Hamilton

Jason Corbett

A method of determining particle size distribution from multi-angle dynamic light scattering data, comprising: obtaining a series of measured correlation functions g(&#x3b8;) at scattering angles &#x3b8;; and solving an equation comprising wherein: K(&#x3b8;) is the instrument scattering matrix computed for angle i, x is the particle size distribution, and &#x3b1;is the scaling coefficient for angle i. The method comprises using the steps: a) providing initial estimates for scaling factors &#x3b1;to &#x3b1;, and defining &#x3b1;=1; b) iterating scaling factors &#x3b1;to &#x3b1;using a non-linear solver; c) solving for x using a linear solver; d) calculate residual; e) repeat steps b) to d) while the residual is greater than a predefined exit tolerance.

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Malvern, United Kingdom

Douglas Hamilton