Molecular Genetics Research and Development Limited Partnership

Douglas F Harbrecht

John S Salstrom

Shiu-Lok Hu

Dawn Newman

DNA cloning and expression vectors capable of replication in a microbial host comprising from upstream to downstream (a) at least one promoter; (b) a translation start codon; (c) a cloning segment which provides a means for inserting nucleic acid sequences and (d) a sequence coding for a detectable gene product, out of translational phase with the translation start codon but capable of being readjusted to the translational phase of said start codon by insertion into the cloning segment of nucleic acid sequences containing the proper number of nucleotides for readjustment, said gene product providing a means for detecting expression of inserted nucleic acid sequences.

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Hopkins, MN, United States of America

Douglas F Harbrecht