Pfizer Corporation

Douglas Carl Behenna

Kevin Daniel Freeman-Cook

Asako Nagata

Sacha Ninkovic

Robert Louis Hoffman

Sajiv Krishnan Nair

Cynthia Louise Palmer

Scott Channing Sutton

Mehran Jalaie

Eugene Yuanjin Rui

Ping Chen

Martha Alicia Ornelas

Robert Steven Kania

Kimberly O Cameron

John Charles Kath

Hengmiao Cheng

Samit Kumar Bhattacharya

Liying Zhang

Martin Youngjin Pettersson

Theodore Otto Johnson, Jr

John M Curto

Matthew Forrest Sammons

Qingyi Yang

Simon Paul Planken

Yajing Lian

Sujin Cho-Schultz

Theodore Otto Johnson

Theodore Otto Johnson Jr

This invention relates to compounds of Formula (I)

CDK2 inhibitors

This invention relates to compounds of Formula (I) and enantiomers thereof, and to pharmaceutically acceptable salts of Formula (I) and said enantiomers, wherein R, Rand Rare as defined herein. The invention further relates to pharmaceutical compositions comprising such compounds and salts, and to methods and uses of such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer, in a subject in need thereof.

This invention relates to compounds of general Formula (I) 

CDK2/4/6 inhibitors

This invention relates to compounds of general Formula I in which A, R, R, Rand Rare as defined herein, and the pharmaceutically acceptable salts thereof; to pharmaceutical compositions comprising such compounds and salts; to methods of using such compounds, salts and compositions for treating pulmonary hypertension and related diseases, like pulmonary arterial hypertension; to methods of using such compounds, salts and compositions for treating abnormal cell growth, such as cancer; and to processes to make such compounds, salts and compositions.

Anti-proliferative agents for treating PAH

This invention relates to compounds of Formula (I) 

The present invention relates to compounds of formula (I) 

Purine derivatives

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San Juan Capistrano, CA, United States of America

Douglas Carl Behenna